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Merck
CN

80154

邻苯二甲酸二戊酯

Selectophore, ≥99.0%

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经验公式(希尔记法):
C18H26O4
化学文摘社编号:
分子量:
306.40
UNSPSC Code:
26111700
NACRES:
NB.61
PubChem Substance ID:
EC Number:
205-017-9
Beilstein/REAXYS Number:
1987323
MDL number:
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description

for ion-selective electrodes

Quality Level

product line

Selectophore

assay

≥99.0% (GC), ≥99.0%

form

liquid

refractive index

n20/D 1.490

density

1.025 g/mL at 20 °C (lit.)

SMILES string

CCCCCOC(=O)c1ccccc1C(=O)OCCCCC

InChI

1S/C18H26O4/c1-3-5-9-13-21-17(19)15-11-7-8-12-16(15)18(20)22-14-10-6-4-2/h7-8,11-12H,3-6,9-10,13-14H2,1-2H3

InChI key

IPKKHRVROFYTEK-UHFFFAOYSA-N

General description

Dipentyl phthalate (DPeP) belongs to phthalate group, and is a dialkyl or aryl/alkyl diesters of phthalic acid. It may be prepared from phthalic anhydride along with n-pentanol.
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Application


  • Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats: Dipentyl phthalate′s structural similarities to DINP underpin studies on phthalate exposure′s impacts on male reproductive health, providing insights into potential risks and mechanisms of toxicity in developmental stages (Earl Gray L Jr, 2023).

  • Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation: This study uses dipentyl phthalate to examine the adverse effects of phthalate exposure on adrenal gland function, contributing to a deeper understanding of metabolic disruptions (Chen et al., 2023).

  • Determination of 15 phthalic acid esters based on GC-MS/MS coupled with modified QuEChERS in edible oils: This research demonstrates the utility of dipentyl phthalate in method development for detecting phthalates in food matrices, enhancing food safety assessments (Wang et al., 2022).

  • Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development: Dipentyl phthalate is investigated for its role in developmental toxicity, aiding in the construction of models predicting reproductive health effects from chemical exposures (Palermo et al., 2021).

Other Notes

用于 PVC 膜电极的增塑剂

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazardEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

244.4 °F - closed cup

flash_point_c

118 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M.M. Khalil
Analytical Letters, 26, 2071-2071 (1993)
D M Creasy et al.
Experimental and molecular pathology, 46(3), 357-371 (1987-06-01)
A sequential morphological study has been carried out to examine the ultrastructural effects of di-n-pentyl phthalate (DPP) on the mature rat testis. A single oral dose of 2.2 g DPP/kg body wt was administered, and testes, perfuse-fixed 3-48 hr after
N P Moore et al.
Archives of toxicology, 66(6), 435-442 (1992-01-01)
Cell-specific testicular toxicants have been used to examine the distribution of creatine within the rat testis, and to examine the potential use of creatinuria as a non-invasive indicator of testicular damage. Groups of rats were administered single doses of various



全球贸易项目编号

货号GTIN
80154-5ML04061832974484
80154-1ML04061837879418