80709
隐丹参酮
analytical standard
别名:
(R)-(−)-1,6,6-三甲基-1,2,6,7,8,9-六氢菲并[1,2-b]呋喃-10,11-二酮, 丹参酮C
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关于此项目
经验公式（希尔记法）:
C19H20O3
化学文摘社编号:
分子量:
296.36
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5445400
产品名称
隐丹参酮, analytical standard
InChI
1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
SMILES string
C[C@H]1COC2=C1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23
InChI key
GVKKJJOMQCNPGB-JTQLQIEISA-N
grade
analytical standard
assay
≥97.0% (HPLC)
optical activity
[α]/D -85.0±3.0°, c = 0.1 in chloroform
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
隐丹参酮可作为分析参考标准品，通过不同色谱技术对生物学样品和药物制剂中的分析物进行定量。
Biochem/physiol Actions
隐丹参酮是一种最初是从丹参根中提取的抗菌和抗炎化合物。 隐丹参酮已被发现可抑制HIF的活化以及巨噬细胞迁移，对PI3K通路实现负调控。它对数种金黄色葡萄球菌菌株具有活性。
General description
隐丹参酮是一种从丹参中分离得到生物活性物质，属于丹参酮类化合物，具有抗菌、抗炎、抗肿瘤等多种广谱治疗作用。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Simultaneous determination of danshensu, ferulic acid, cryptotanshinone and tanshinone IIA in rabbit plasma by HPLC and their pharmacokinetic application in danxiongfang
Li X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 44(5), 1106-1112 (2007)
Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC
Shi Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(3), 481-486 (2005)
Shuangtao Ma et al.
Molecular medicine reports, 6(1), 145-150 (2012-04-17)
Cryptotanshinone is an active ingredient of Salvia miltiorrhiza that has been used in traditional Chinese medicine for treating cardiovascular disorders. Thus, we investigated the effects of cryptotanshinone on cardiac fibrosis induced by isoprenaline and examined whether cardiac matrix metalloproteinase (MMP)-2
Wenxing Chen et al.
Cancer prevention research (Philadelphia, Pa.), 5(5), 778-787 (2012-04-12)
Cryptotanshinone (CPT), a natural compound isolated from the plant Salvia miltiorrhiza Bunge, is a potential anticancer agent. However, the underlying mechanism is not well understood. Here, we show that CPT induced caspase-independent cell death in human tumor cells (Rh30, DU145
Yingjie Wei et al.
Molecules (Basel, Switzerland), 17(7), 8617-8632 (2012-07-20)
The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI) were selected as model compounds
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