80714
丹参酮 I
analytical standard
别名:
丹参酮 Ⅰ, 丹参酮A, 丹参醌 I
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关于此项目
经验公式（希尔记法）:
C18H12O3
化学文摘社编号:
分子量:
276.29
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
InChI
1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3
SMILES string
Cc1coc2-c3ccc4c(C)cccc4c3C(=O)C(=O)c12
InChI key
AIGAZQPHXLWMOJ-UHFFFAOYSA-N
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
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General description
丹参酮I是一种生物成分，属于从丹参中分离的丹参酮化合物。它通常用于扩张冠状动脉，增加冠状动脉血流量，调节诱变活性并保护心肌免受缺血。
Application
丹参酮I可用作分析参考标准品，用于通过不同的色谱技术对丹参根和药物制剂中的分析物进行定量。
有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
中药丹参（Salvia miltiorrhiza）中的菲醌成分。 通过调节粘附分子来调节或预防乳腺癌转移。抗炎症。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Development of the fingerprints for the quality of the roots of Salvia miltiorrhiza and its related preparations by HPLC-DAD and LC-MSn
Liu H-A, et al.
Journal of Chromatography. B, Biomedical Applications, 846(1-2), 32-41 (2007)
Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC
Shi Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(3), 481-486 (2005)
Wen-Quan Wang et al.
Journal of hematology & oncology, 5, 69-69 (2012-11-10)
Promotion of endothelial normalization restores tumor oxygenation and obstructs tumor cells invasion, intravasation, and metastasis. We therefore investigated whether a vasoactive drug, tanshinone IIA, could inhibit metastasis by inducing vascular normalization after palliative resection (PR) of hepatocellular carcinoma (HCC). A
Qing Cai et al.
Chinese journal of integrative medicine, 18(11), 837-845 (2012-10-23)
To investigate the protective effects of sodium tanshinone B (STB) on brain damage following focal ischemia-reperfusion (I/R) injury through interfering with N-methyl-D-aspartic acid receptor (NMDAR) and excitatory and inhibitory amino acids, and evaluate the potential mechanisms of the neuroprotective activity
Xin Liu et al.
Biomaterials, 34(3), 817-830 (2012-11-01)
Tanshinone IIA is a good candidate for treating cerebral ischemia, but its short half-life and poor permeability across the blood-brain-barrier (BBB) limit its curative efficacy. In this study, we successfully developed cationic bovine serum albumin-conjugated tanshinone IIA PEGylated nanoparticles (CBSA-PEG-TIIA-NPs).
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