83700
罗丹宁
for spectrophotometric det. of gallic acid, ≥99.0%
别名:
2-硫代-4-噻唑烷酮
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关于此项目
经验公式（希尔记法）:
C3H3NOS2
化学文摘社编号:
分子量:
133.19
UNSPSC Code:
12352200
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-505-1
Beilstein/REAXYS Number:
110701
MDL number:
Assay:
≥99.0% (HPLC), ≥99.0%
Form:
crystals
InChI key
KIWUVOGUEXMXSV-UHFFFAOYSA-N
InChI
1S/C3H3NOS2/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
SMILES string
O=C1CSC(=S)N1
assay
≥99.0% (HPLC), ≥99.0%
form
crystals
quality
for spectrophotometric det. of gallic acid
technique(s)
UV/Vis spectroscopy: suitable
mp
165-169 °C (lit.), 165-169 °C
solubility
methanol: 0.5 g/10 mL, clear, colorless to greenish-yellow
Quality Level
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Other Notes
用于重量分析测定银的试剂；用于没食子酸的分光光度测定
General description
Rhodanine is a drug, which prevents the multiplication of echovirus 12.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Selective inhibition of uncoating of echovirus 12 by rhodanine A study on early virus-cell interactions
Eggers, Hans J
Virology, 78(1), 241-252 (1977)
M. Thies et al.
Mikrochimica Acta, 809-809 (1973)
Matjaž Brvar et al.
Bioorganic & medicinal chemistry, 20(8), 2572-2580 (2012-03-27)
Bacterial DNA gyrase is an established and validated target for the development of novel antibacterials. In our previous work, we identified a novel series of bacterial gyrase inhibitors from the class of 4-(2,4-dihydroxyphenyl) thiazoles. Our ongoing effort was designated to
Parminder Singh et al.
Biochemistry, 51(27), 5434-5442 (2012-06-19)
A perturbation of FtsZ assembly dynamics has been shown to inhibit bacterial cytokinesis. In this study, the antibacterial activity of 151 rhodanine compounds was assayed using Bacillus subtilis cells. Of 151 compounds, eight strongly inhibited bacterial proliferation at 2 μM.
Ming-Xia Song et al.
European journal of medicinal chemistry, 54, 403-412 (2012-06-19)
Five series of (Z)-5-(4-(2-oxo-2-phenylethoxy)benzylidene)-2-thioxothiazolidin-4-one derivatives (I-V) were synthesized, characterized, and evaluated for their anti-bacterial activity. Most of the synthesized compounds showed potent inhibition against several Gram-positive bacteria (including multidrug-resistant clinical isolates) with MIC values in the range of 1-32 μg/mL.
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