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线性分子式:
HOCH(COOH)2
化学文摘社编号:
分子量:
120.06
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-301-1
Beilstein/REAXYS Number:
1209791
MDL number:
Assay:
≥97.0%
Form:
powder
InChI key
ROBFUDYVXSDBQM-UHFFFAOYSA-N
InChI
1S/C3H4O5/c4-1(2(5)6)3(7)8/h1,4H,(H,5,6)(H,7,8)
SMILES string
OC(C(O)=O)C(O)=O
assay
≥97.0%
form
powder
mp
158-160 °C (dec.) (lit.)
functional group
carboxylic acid, hydroxyl
storage temp.
2-8°C
Application
- 用于改善热导率的聚合物的合成:在聚合物合成中研究人员采用羟基丙二酸来探索酶反应,显著提高了材料的热导率,这对制造和材料科学应用很关键(Nan et al., 2023)。
- 绿色化学处理中的进展:这种酸在甘油废物处理的电氧化途径中起一定作用,为可持续化学过程和绿色化学应用做出贡献,这对减轻环境影响至关重要(Cheng et al., 2021)。
- 生物柴油副产物处理的发展:羟基丙二酸也涉及生物柴油生产副产物甘油的电化学转化的动力学研究,该研究彰显了其在可再生能源和废物增值的作用(Pérès et al., 2020)。
- 无碱氧化反应: 它有助于开发铂催化剂催化的甘油转化为甘油醛的无碱氧化反应条件,为催化和有机合成过程领域带来进步(Capron et al., 2019)。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
G Gutierrez et al.
Journal of applied physiology (Bethesda, Md. : 1985), 76(6), 2735-2741 (1994-06-01)
Lactate uptake by skeletal muscle occurs under diverse conditions, including hypoxia and electrical stimulation. A possible metabolic fate of lactate in resting muscle is its conversion to pyruvate followed by carboxylation to malate in the cytosolic malic reaction. To test
A Shah et al.
Bioorganic & medicinal chemistry, 5(2), 323-334 (1997-02-01)
A new, aromatic analogue of the EPSP synthase enzyme reaction intermediate 1 has been identified, which contains a 3-hydroxymalonate moiety in place of the usual 3-phosphate group. This simplified inhibitor was readily prepared in five steps from ethyl 3,4-dihydroxybenzoate. The
S H Park et al.
Biochemistry, 23(23), 5446-5453 (1984-11-06)
Measurement of the initial rate of the malic enzyme reaction varying the concentration of NAD at several different fixed levels of Mg2+ (0.25-1.0 mM) and a single malate concentration gave a pattern which intersects to the left of the ordinate.
A Cortés et al.
The Biochemical journal, 357(Pt 1), 263-268 (2001-06-21)
The concentration of an inhibitor that decreases the rate of an enzyme-catalysed reaction by 50%, symbolized i(0.5), is often used in pharmacological studies to characterize inhibitors. It can be estimated from the common inhibition plots used in biochemistry by means
J Klimek et al.
Journal of steroid biochemistry, 26(1), 161-163 (1987-01-01)
It has been shown that the conversion of cholesterol to progesterone by human term placental mitochondria incubated in the presence of malate or fumarate was inhibited by hydroxymalonate--an inhibitor of malic enzyme. No inhibition was observed when mitochondria were incubated
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