89397
吉拉尔特试剂 T
derivatization grade (HPLC), LiChropur™, 99.0-101.0% (AT)
别名:
(羧甲基)三甲基氯化铵酰肼, 乙酰肼三甲基氯化铵, 氯化三甲基铵乙酰肼
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关于此项目
线性分子式:
[(CH3)3N+CH2CONHNH2]Cl-
化学文摘社编号:
分子量:
167.64
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-629-3
Beilstein/REAXYS Number:
3727163
MDL number:
grade
derivatization grade (HPLC)
Quality Segment
assay
99.0-101.0% (AT)
form
crystals
quality
LiChropur™
technique(s)
HPLC: suitable
mp
188-192 °C (dec.) (lit.)
SMILES string
[Cl-].C[N+](C)(C)CC(=O)NN
InChI
1S/C5H13N3O.ClH/c1-8(2,3)4-5(9)7-6;/h4,6H2,1-3H3;1H
InChI key
YSULOORXQBDPCU-UHFFFAOYSA-N
Application
Girard′s reagent T may be used as a derivatizing reagent for the determination of 5-Formyl-2′-deoxyuridine in cellular DNA samples using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique. Reducing saccharides can be derivatized by Girard′s reagent T and this can be analyzed by matrix-assisted laser desorption/ionization coupled to time of flight mass spectrometry (MALDI-TOF-MS) technique.
Features and Benefits
- Girard′s reagent T is a chemical derivatization reagent for LC-MS.
- It has carbonyl functional group possessing high proton (cation) affinity that stabilizes a positive charge.
- It is commonly used in the derivatization of nucleosides.
- Derivatization reactions in mass spectrometry are used to improve ionization efficiency.
- Derivatization can enhance precise quantitative analysis for profiling of relatively small analyte molecules, particularly in metabolomics.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable