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Merck
CN

89773

亚细亚酸

analytical standard

别名:

2α, 23-二羟基熊果酸, NSC 166063, 达玛醇酸

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关于此项目

经验公式(希尔记法):
C30H48O5
化学文摘社编号:
分子量:
488.70
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
482-720-9
MDL number:
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grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

325-330 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O

InChI

1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1

InChI key

JXSVIVRDWWRQRT-UYDOISQJSA-N

Application

Asiatic acid (AA) has been used in a study to investigate its antihypertensive effect in high carbohydrate, high fat (HCHF) diet-induced MS metabolic syndrome (MS) rats. It has also been used in a study to understand its chemoprophylaxis effect against malaria in Sprague-Dawley rats.
积雪草酸衍生物合成的起始物料:
  • 抗癌药
  • 糖原磷酸化酶抑制剂
  • 肝保护剂
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

积雪草酸常用于伤口愈合。积雪草酸具有抗氧化、抗炎和神经保护属性


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Asiatic acid attenuates renin-angiotensin system activation and improves vascular function in high-carbohydrate, high-fat diet fed rats
Putcharawipa M, et al.
BMC Complementary and Alternative Medicine, 16(1), 1-1 (2016)
Pre-infection administration of asiatic acid retards parasitaemia induction in Plasmodium berghei murine malaria infected Sprague-Dawley rats.
Mavondo GA, et al.
Malaria Journal, 15(1), 1-1 (2016)
Wenjie Guo et al.
International immunopharmacology, 24(2), 232-238 (2014-12-20)
In the present study, the effect of asiatic acid, a natural triterpenoid compound, on murine experimental colitis induced by dextran sulfate sodium (DSS) and its possible mechanism were examined in vivo and vitro. Oral administration of asiatic acid dose-dependently attenuated



全球贸易项目编号

货号GTIN
89773-10MG04061833076675