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Merck
CN

90210

D-(+)-海藻糖 二水合物

≥99.0%, suitable for microbiology, composed of two α-glucose units that is used as a protectant, stabilizer and to support proper folding

别名:

海藻糖二水合物，a-d-吡喃葡萄糖基a-d-吡喃葡萄糖苷, α,α-海藻糖, α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷

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关于此项目

经验公式（希尔记法）:
C12H22O11 · 2H2O
化学文摘社编号:
6138-23-4
分子量:
378.33
UNSPSC Code:
41106212
NACRES:
NA.85
PubChem Substance ID:
329769859
EC Number:
202-739-6
Beilstein/REAXYS Number:
5322018
MDL number:
MFCD00071594

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产品名称

D-(+)-海藻糖 二水合物, ≥99.0%, suitable for microbiology, composed of two α-glucose units that is used as a protectant, stabilizer and to support proper folding

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

SMILES string

[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

assay

≥99.0% (HPLC)
≥99.0%

form

powder

optical activity

[α]20/D +176 to +186°, c = 2% in H2O

mol wt

378.33  g/mol

impurities

≤0.1% glucose

ign. residue

≤0.1% (as SO4)

solubility

H2O: 0.1 g/mL, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤0.1 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

application(s)

microbiology

Quality Level

200

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相关类别

Application

D-(+)-海藻糖可被用作某些细胞培养的碳水化合物储备，用以抵御环境压力。 它还可用于作为单克隆抗体生物制药配方的蛋白稳定剂。

General description

D-(+)-海藻糖是由两分子 α-葡萄糖组成的二糖。它在多种细胞冷冻培养基中作为冷冻保护剂。用作运输介质中的保护剂。它主要存在于支持低湿休眠（无水生活）的物种中。它可作为微生物中的碳水化合物储备，并保护它们免受不利条件的影响，如热、冷、脱水、干燥和氧化。海藻糖可以作为影响蛋白质折叠的化学伴侣。已知它可防止产生淀粉样蛋白和 β-淀粉样蛋白堆积。在亨廷顿蛋白聚集中也观察到了海藻糖的类似作用。因此，它可以作为阿尔茨海默氏′病和亨廷顿′病的保护剂。海藻糖能更好的刺激 沙门氏菌 细胞的初期生长。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000514069
0000514069
0000490124
0000490123
0000490124

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Base Ingredients of Microbiology Media

Culture media provides a habitat with suitable nutrients, energy sources, and certain environmental conditions for the growth of microorganisms. The components of the culture media range from simple sugars to peptones, salts, antibiotics, and complex indicators.

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