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Merck
CN

92136

染料木黄酮

analytical standard

别名:

4′,5,7-三羟基异黄酮, 5,7-二羟基-3-(4-羟基苯基)-4H-1-苯并吡喃-4-酮

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关于此项目

经验公式(希尔记法):
C15H10O5
化学文摘社编号:
分子量:
270.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-174-9
Beilstein/REAXYS Number:
263823
MDL number:
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产品名称

染料木黄酮, analytical standard

InChI

1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H

SMILES string

Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O

InChI key

TZBJGXHYKVUXJN-UHFFFAOYSA-N

grade

analytical standard

assay

≥97% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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Application

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。

Biochem/physiol Actions

酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中,ATP的竞争性抑制剂。 抗血管生成剂,可下调参与控制血管生成的基因的转录。

General description

Genistein是一种天然存在的大豆异黄酮,是一种饮食蛋白酪氨酸激酶(PTK抑制剂。目前发现它具有抗癌特性。

Other Notes

这种化合物常见于以下属的植物中:甘草

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Genistein inhibits renal cancer progression through long non-coding RNA HOTAIR suppression
Imai-Sumida M, et al.
Clinical Cancer Research, 3449-3449 (2017)
Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells
GP and SB
Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research, 7, 1345-1351 (1996)
Alexandra Mamagkaki et al.
PloS one, 16(4), e0250599-e0250599 (2021-04-28)
The objective of this study is to improve and optimize the formulation of Genistein in capsules in order to result in a better pharmacokinetic profile comparing to existing commercial products. In order to do this, five different formulations of Genistein
Sonia de Pascual-Teresa et al.
The Journal of nutritional biochemistry, 17(4), 257-264 (2005-08-20)
If soy isoflavones are to be effective in preventing or treating a range of diseases, they must be bioavailable, and thus understanding factors which may alter their bioavailability needs to be elucidated. However, to date there is little information on
I R Rowland et al.
Nutrition and cancer, 36(1), 27-32 (2000-05-08)
The soy isoflavones, daidzein and genistein, and the lignans, matairesinol and secoisolariciresinol, are phytoestrogens metabolized extensively by the intestinal microflora. Considerable important evidence is already available that shows extensive interindividual variation in isoflavone metabolism, and we have investigated the extent

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