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Merck
CN

92817

9-氨基吖啶

suitable for matrix substance for MALDI-MS, ≥99.5% (HPLC)

别名:

9-吖啶胺

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关于此项目

经验公式（希尔记法）:
C13H10N2
化学文摘社编号:
90-45-9
分子量:
194.23
NACRES:
NA.21
PubChem Substance ID:
329770174
UNSPSC Code:
23151816
EC Number:
201-995-6
MDL number:
MFCD00037839

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产品名称

9-氨基吖啶, suitable for matrix substance for MALDI-MS, ≥99.5% (HPLC)

InChI key

XJGFWWJLMVZSIG-UHFFFAOYSA-N

InChI

1S/C13H10N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H,(H2,14,15)

SMILES string

Nc1c2ccccc2nc3ccccc13

assay

≥99.5% (HPLC)

form

powder

analyte functional class(es)

metabolites

analyte chemical class(es)

lipids

technique(s)

MALDI-MS: suitable

impurities

≤0.05% sulfated ash

loss

≤10% loss on drying

mp

238-240 °C

cation traces

Ba: ≤5 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Fe: ≤10 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
K: ≤100 mg/kg
Na: ≤100 mg/kg

suitability

suitable for matrix substance for MALDI-MS

Quality Level

100

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相关类别

Application

MALDI 基质在在负模式下分析低分子量阴离子（如代谢物）时具有背景低和灵敏度好的特点

General description

9-氨基吖啶，一种氨基吖啶染料，可作为病毒和细菌的有效诱变剂。

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN8805
BCCL6577
BCCK5950
BCCJ0256
BCCH0643

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Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl (3'-5') guanosine crystalline complex.
Sakore, T. D., et al.
Proceedings of the National Academy of Sciences of the USA, 74.1, 188-192 (1977)
Daniel J Karst et al.
Biotechnology progress, 33(4), 879-890 (2016-12-21)
Perfusion cell culture processes allow the steady-state culture of mammalian cells at high viable cell density, which is beneficial for overall product yields and homogeneity of product quality in the manufacturing of therapeutic proteins. In this study, the extent of
9-Aminoacridine as a matrix for negative mode matrix-assisted laser desorption/ionization
Vermillion-Salsbury, R. L. and Hercules, D. M.
Rapid Communications in Mass Spectrometry, 16, 1575-1581 (2002)
Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity.
Andrea Amantonico et al.
Angewandte Chemie (International ed. in English), 47(29), 5382-5385 (2008-06-11)
Lulu H Tucker et al.
Analytical chemistry, 91(15), 9522-9529 (2019-07-03)
Multicellular tumor spheroids (MTS) are a well-established model system for drug development and are a valuable in vitro research tool for use prior to employing animal models. These 3D-cell cultures are thought to display chemical gradients of oxygen and nutrients
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