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Merck
CN

92822

苦基磺酸 溶液

1 M in H2O

别名:

2,4,6-三硝基苯磺酸 溶液, TNBS

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关于此项目

经验公式(希尔记法):
C6H3N3O9S
化学文摘社编号:
分子量:
293.17
UNSPSC Code:
12352005
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
572358
Concentration:
1 M in H2O
Form:
liquid
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form

liquid

Quality Level

concentration

1 M in H2O

solubility

water: soluble at 20 °C

density

1.14 g/mL at 20 °C

ε (extinction coefficient)

≤0.85 at 340 nm

shipped in

dry ice

storage temp.

−20°C

SMILES string

OS(=O)(=O)c1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18)

InChI key

NHJVRSWLHSJWIN-UHFFFAOYSA-N

Application

亲水改性剂。 具有氨基化合物的衍生物可以通过肼进行再生。
苦味磺酸(2,4,6-三硝基苯磺酸溶液,TNBS)可用于研究细胞内pH的调节机制。 TNBS可用于诱发炎症性肠病(IBD)/结肠炎,从而用于其机理和治疗方法的研究。

Other Notes

销售限制可能适用

Disclaimer

在≥0°C下保存时会发生降解,并形成沉淀(苦味酸)


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Desen. Expl. 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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A Arranz et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 163-172 (2012-11-28)
CD40-CD40L interactions appear to play an important role in the pathogenesis of experimental colitis. We tested the effect and investigated the underlying mechanism of action of systemically administered antisense oligonucleotide (ASO) targeting CD40 formulated in amphoteric liposomes (nov038/CD40). The charge
Carla Petrella et al.
Pharmacological research, 70(1), 72-79 (2013-01-29)
Nociceptin/orphanin FQ (N/OFQ) and nociceptin orphanin peptide (NOP) receptors represent an endogenous system modulating gastrointestinal functions and inflammation. We investigated the peripheral effect of N/OFQ and of UFP-101, the NOP antagonist, in a model of colitis induced by TNBS (2,4,6
Zhen Huang et al.
Gut, 63(8), 1247-1257 (2013-09-04)
Emerging evidence suggests that microRNA (miRNA)-mediated gene regulation influences a variety of autoimmune disease processes, including Crohn's disease (CD), but the biological function of miRNAs in CD remains unclear. We examine miRNA level in colon tissues and study the potential



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