93103
Paraoxon-ethyl-d10 (diethyl-d10)
PESTANAL®, analytical standard
别名:
O,O-Diethyl-d10 O-(4-nitrophenyl) phosphate, Diethyl-d10 p-nitrophenyl phosphate, Ethyl-d10 paraoxon
grade
analytical standard
product line
PESTANAL®
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
application(s)
agriculture
format
neat
storage temp.
2-8°C
Quality Level
General description
Paraoxon-ethyl-d10 (diethyl-d10) is an isotope-labeled analog of organophosphate pesticide paraoxon, wherein the diethoxy protons are replaced by deuterium.
Application
Paraoxon-ethyl-d10 (diethyl-d10) may be used as a deuterated internal standard to quantify the paraoxon-ethyl in animal biological samples by liquid chromatography-high resolution mass spectrometry (LC-HRMS) technique.
Isotope-labeled compounds are increasingly used in isotope dilution mass spectrometry (IDMS) for the quantitative analysis of pesticides. The major advantage of using this technique is that the isotope-labeled compounds have nearly the same physical properties as their non-labeled counterpart analogs, and thus show identical behavior during the workup and sample preparation process. This helps in overcoming the problems of matrix effects generally encountered in the usual LC-MS/GC-MS analysis potentially resulting in biased results. By spiking the sample before workup with its isotope labeled analog, the loss of analyte that leads to matrix effects can be determined and compensated.
Isotope-labeled compounds are increasingly used in isotope dilution mass spectrometry (IDMS) for the quantitative analysis of pesticides. The major advantage of using this technique is that the isotope-labeled compounds have nearly the same physical properties as their non-labeled counterpart analogs, and thus show identical behavior during the workup and sample preparation process. This helps in overcoming the problems of matrix effects generally encountered in the usual LC-MS/GC-MS analysis potentially resulting in biased results. By spiking the sample before workup with its isotope labeled analog, the loss of analyte that leads to matrix effects can be determined and compensated.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Enzyme-free electrochemical detection of nanomolar levels of the organophosphorus pesticide paraoxon-ethyl by using a poly (N-isopropyl acrylamide)-chitosan microgel decorated with palladium nanoparticles
Mutharani B, et al.
Microchimica Acta, 186(3), 1-11 (2019)
Interaction of Cucurbit [7] uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?
Zdarova K, et al.
International Journal of Molecular Sciences, 21(21), 7883-7883 (2020)
4-Hydroxyestrone, an Endogenous Estrogen Metabolite, Can Strongly Protect Neuronal Cells Against Oxidative Damage
Choi HJ, et al.
Scientific reports, 10(1), 1-15 (2020)
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