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Merck
CN

93129

Supelco

Piperacillin sodium salt

analytical standard

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关于此项目

经验公式(希尔记法):
C23H26N5NaO7S
化学文摘社编号:
分子量:
539.54
Beilstein:
5373920
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥94% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)c4ccccc4)C(=O)C1=O

InChI

1S/C23H27N5O7S.Na/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);/q;+1/p-1/t13-,14-,15+,20-;/m1./s1

InChI key

WCMIIGXFCMNQDS-IDYPWDAWSA-M

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一般描述

Piperacillin sodium is a semi-synthetic penicillin which belongs to the β-lactam class of antibiotics with a broad spectrum of antibacterial activity against anaerobic pathogens and both gram positive and gram negative bacteria.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Piperacillin therapy for serious bacterial infections.
Winston DJ, et al.
The American Journal of Medicine, 69(2), 255-261 (1980)
Piperacillin sodium: antibacterial spectrum, pharmacokinetics, clinical efficacy, and adverse reactions.
Fortner CL, et al.
Pharmacotherapy, 2(6), 287-298 (1982)
Chandra Datta Sumi et al.
The Journal of antimicrobial chemotherapy, 75(9), 2633-2640 (2020-06-26)
To compare bacterial killing and the emergence of resistance to piperacillin/tazobactam, administered by intermittent versus prolonged infusion (i.e. extended or continuous), for ceftriaxone-resistant Klebsiella pneumoniae clinical isolates in an in vitro dynamic hollow-fibre infection model (HFIM). K. pneumoniae 68 (Kp68;
Erlangga Yusuf et al.
Journal of critical care, 29(6), 1089-1095 (2014-09-03)
The purpose of this study is to review the rationale of prolonged (ie, extended or continuous) infusion of piperacillin/tazobactam (PIP/TAZ) in critically ill patients and to perform a systematic review that compare the effectiveness of prolonged infusion with intermittent bolus
T W Felton et al.
Clinical pharmacology and therapeutics, 96(4), 438-448 (2014-06-14)
Pulmonary infections in critically ill patients are common and are associated with high morbidity and mortality. Piperacillin-tazobactam is a frequently used therapy in critically ill patients with pulmonary infection. Antibiotic concentrations in the lung reflect target-site antibiotic concentrations in patients

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