93650
色胺 盐酸盐
≥98.0% (AT)
别名:
β-吲哚基乙胺 盐酸盐, 3-(2-氨乙基)吲哚 盐酸盐
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选择尺寸
关于此项目
经验公式（希尔记法）:
C10H12N2 · HCl
化学文摘社编号:
分子量:
196.68
MDL number:
EC Number:
206-446-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3568419
InChI key
KDFBGNBTTMPNIG-UHFFFAOYSA-N
InChI
1S/C10H12N2.ClH/c11-6-5-8-7-12-10-4-2-1-3-9(8)10;/h1-4,7,12H,5-6,11H2;1H
SMILES string
Cl[H].NCCc1c[nH]c2ccccc12
assay
≥98.0% (AT)
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Application
反应物用于制备：
- 抑制乙型肝炎病毒的色胺衍生物
- 作为潜在的抗肿瘤药物的氨甲酰基表鬼臼毒素
- 作为 CCK 受体拮抗剂的邻氨基苯甲酸衍生物
- 作为吲哚胺 2,3-双加氧酶抑制剂的油菜素衍生物
- 解痉剂
- 作为新型抗疟药物的β -卡波林阳离子
Biochem/physiol Actions
具有血管活性；可能具有神经调质功能。
Other Notes
用于芳基胺 N-甲基转移酶测定的底物；也用于测定组织匀浆中的单胺氧化酶的活性
由色氨酸经 L-芳香氨基酸脱羧酶作用进行脱羧而形成的生物胺。
法规信息
新产品
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Arylamine N-methyltransferase.
E S Lyon et al.
Methods in enzymology, 77, 263-266 (1981-01-01)
S.H. Snyder et al.
Methods in Enzymology, 17B, 741-741 (1971)
Gabriele Loers et al.
Journal of neurochemistry, 128(1), 88-100 (2013-08-21)
Polysialic acid (PSA) is a major regulator of cell-cell interactions in the developing nervous system and in neural plasticity in the adult. As a polyanionic molecule with high water-binding capacity, PSA increases the intercellular space generating permissive conditions for cell
Xiangbing Qi et al.
Journal of the American Chemical Society, 133(26), 10050-10053 (2011-06-16)
We report the first total synthesis of (±)-trigonoliimine C, a member of a family of structurally complex alkaloids, in 10 steps from tryptamine and 6-methoxytryptamine. Our convergent synthetic strategy relies on a selective oxidative rearrangement of an unsymmetrical 2,2'-bis-tryptamine.
Quanli Gu et al.
The Journal of chemical physics, 137(10), 104312-104312 (2012-09-18)
The relative ionization energies of tryptamine conformations are determined by zero kinetic energy photoelectron spectroscopy and photoionization efficiency measurements. The relative cationic conformational stabilities are compared to the published results for the neutral molecule. In the cation, the interaction strength
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