93650
色胺 盐酸盐
≥98.0% (AT)
别名:
β-吲哚基乙胺 盐酸盐, 3-(2-氨乙基)吲哚 盐酸盐
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选择尺寸
关于此项目
经验公式（希尔记法）:
C10H12N2 · HCl
化学文摘社编号:
分子量:
196.68
MDL number:
EC Number:
206-446-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3568419
InChI key
KDFBGNBTTMPNIG-UHFFFAOYSA-N
InChI
1S/C10H12N2.ClH/c11-6-5-8-7-12-10-4-2-1-3-9(8)10;/h1-4,7,12H,5-6,11H2;1H
SMILES string
Cl[H].NCCc1c[nH]c2ccccc12
assay
≥98.0% (AT)
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Application
反应物用于制备：
- 抑制乙型肝炎病毒的色胺衍生物
- 作为潜在的抗肿瘤药物的氨甲酰基表鬼臼毒素
- 作为 CCK 受体拮抗剂的邻氨基苯甲酸衍生物
- 作为吲哚胺 2,3-双加氧酶抑制剂的油菜素衍生物
- 解痉剂
- 作为新型抗疟药物的β -卡波林阳离子
Biochem/physiol Actions
具有血管活性；可能具有神经调质功能。
Other Notes
用于芳基胺 N-甲基转移酶测定的底物；也用于测定组织匀浆中的单胺氧化酶的活性
由色氨酸经 L-芳香氨基酸脱羧酶作用进行脱羧而形成的生物胺。
法规信息
新产品
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Arylamine N-methyltransferase.
E S Lyon et al.
Methods in enzymology, 77, 263-266 (1981-01-01)
S.H. Snyder et al.
Methods in Enzymology, 17B, 741-741 (1971)
Xianrong Xing et al.
Biosensors & bioelectronics, 31(1), 277-283 (2011-11-15)
An imprinted electrochemical sensor based on polypyrrole-sulfonated graphene (PPy-SG)/hyaluronic acid-multiwalled carbon nanotubes (HA-MWCNTs) for sensitive detection of tryptamine was presented. Molecularly imprinted polymers (MIPs) were synthesized by electropolymerization using tryptamine as the template, and para-aminobenzoic acid (pABA) as the monomer.
Xiangbing Qi et al.
Journal of the American Chemical Society, 133(26), 10050-10053 (2011-06-16)
We report the first total synthesis of (±)-trigonoliimine C, a member of a family of structurally complex alkaloids, in 10 steps from tryptamine and 6-methoxytryptamine. Our convergent synthetic strategy relies on a selective oxidative rearrangement of an unsymmetrical 2,2'-bis-tryptamine.
6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein.
Glaucio Valdameri et al.
ChemMedChem, 7(7), 1177-1180 (2012-05-23)
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