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Merck
CN

B0301

Sigma-Aldrich

生物素

meets USP testing specifications

别名:

D-生物素, Bios II, 维生素B7, 维生素H, 辅酶 R

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关于此项目

经验公式(希尔记法):
C10H16N2O3S
CAS Number:
分子量:
244.31
Beilstein:
86838
EC 号:
MDL编号:
UNSPSC代码:
12352201
eCl@ss:
34058011
PubChem化学物质编号:
NACRES:
NA.21
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生物来源

synthetic (organic)

质量水平

Agency

meets USP testing specifications

方案

97.5-102.0%

表单

powder

颜色

white

mp

231-233 °C (lit.)

应用

pharmaceutical (small molecule)

储存温度

2-8°C

SMILES字符串

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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应用

<ul>
<li><strong>蛋白质生物素化研究:</strong>研究人员正在利用生物素来开发蛋白质中生物素化位点表征的先进策略,研究改善了对于生化研究和药物开发都很关键的蛋白质修饰技术的精确度(Zhu, 2024)。</li>
</ul>

生化/生理作用

对于氨基酸、能量代谢和脂肪酸合成有重要作用的必要维生素。它是四种哺乳类动物羧化酶中的辅基,促进二氧化碳的结合与输送。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Konstantinos Ampatzis et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(26), 10875-10886 (2013-06-28)
In vertebrates, spinal circuits drive rhythmic firing in motoneurons in the appropriate sequence to produce locomotor movements. These circuits become active early during development and mature gradually to acquire the flexibility necessary to accommodate the increased behavioral repertoire of adult
Stuart Trenholm et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14927-14938 (2013-09-13)
Recently, we demonstrated that gap junction coupling in the population of superior coding ON-OFF directionally selective ganglion cells (DSGCs) genetically labeled in the Hb9::eGFP mouse retina allows the passage of lateral anticipatory signals that help track moving stimuli. Here, we
Shigehiro Takahashi et al.
Analytical and bioanalytical chemistry, 402(5), 1749-1758 (2011-08-26)
In this review, the preparation and properties of protein architectures constructed by layer-by-layer (LbL) deposition through avidin-biotin and concanavalin A (Con A)-sugar interactions are discussed in relation to their use for optical and electrochemical biosensors. LbL films can be constructed
Tazu Aoki et al.
Neuron, 78(5), 881-894 (2013-05-21)
The encoding of long-term associative memories for learned behaviors is a fundamental brain function. Yet, how behavior is stably consolidated and retrieved in the vertebrate cortex is poorly understood. We trained zebrafish in aversive reinforcement learning and measured calcium signals
Belén Pérez-Dueñas et al.
Pediatrics, 131(5), e1670-e1675 (2013-04-17)
Thiamine transporter-2 deficiency is a recessive disease caused by mutations in the SLC19A3 gene. Patients manifest acute episodes of encephalopathy; symmetric lesions in the cortex, basal ganglia, thalami or periaqueductal gray matter, and a dramatic response to biotin or thiamine.

商品

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

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