B0301
生物素
meets USP testing specifications
别名:
D-生物素, Bios II, 维生素B7, 维生素H, 辅酶 R
生物来源
synthetic (organic)
质量水平
Agency
meets USP testing specifications
方案
97.5-102.0%
表单
powder
颜色
white
mp
231-233 °C (lit.)
应用
pharmaceutical (small molecule)
储存温度
2-8°C
SMILES字符串
[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
InChI
1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChI key
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
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应用
<ul>
<li><strong>蛋白质生物素化研究：</strong>研究人员正在利用生物素来开发蛋白质中生物素化位点表征的先进策略，研究改善了对于生化研究和药物开发都很关键的蛋白质修饰技术的精确度(Zhu, 2024)。</li>
</ul>
<li><strong>蛋白质生物素化研究：</strong>研究人员正在利用生物素来开发蛋白质中生物素化位点表征的先进策略，研究改善了对于生化研究和药物开发都很关键的蛋白质修饰技术的精确度(Zhu, 2024)。</li>
</ul>
生化/生理作用
对于氨基酸、能量代谢和脂肪酸合成有重要作用的必要维生素。它是四种哺乳类动物羧化酶中的辅基，促进二氧化碳的结合与输送。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
John J Tukker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(16), 6809-6825 (2013-04-19)
Hippocampal CA3 area generates temporally structured network activity such as sharp waves and gamma and theta oscillations. Parvalbumin-expressing basket cells, making GABAergic synapses onto cell bodies and proximal dendrites of pyramidal cells, control pyramidal cell activity and participate in network
Tim J Viney et al.
Nature neuroscience, 16(12), 1802-1811 (2013-10-22)
Hippocampal sharp waves are population discharges initiated by an unknown mechanism in pyramidal cell networks of CA3. Axo-axonic cells (AACs) regulate action potential generation through GABAergic synapses on the axon initial segment. We found that CA3 AACs in anesthetized rats
Adeline Huiling Loo et al.
Nanoscale, 5(17), 7844-7848 (2013-07-13)
Graphene related materials have been widely employed as highly efficient transducers for biorecognition. Here we show a conceptually new approach of using graphene oxide nanoplatelets (50 × 50 nm) as voltammetric inherently active labels for specific protein-target molecule recognition. This
A Limat et al.
Archives of dermatological research, 288(1), 31-38 (1996-01-01)
In humans and in animals, biotin deficiency causes pathological changes in the skin and its appendages. High doses of biotin may also have beneficial effects on skin, hair and fingernails in humans and animals with normal biotin status. Therefore, we
Tuncay Baubec et al.
Cell, 153(2), 480-492 (2013-04-16)
To gain insight into the cellular readout of DNA methylation, we established a strategy for systematically profiling the genome-wide distribution of chromatin-interacting factors. This enabled us to create genomic maps for the methyl-CpG-binding domain (MBD) family of proteins, including disease-relevant
商品
Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
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