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Merck
CN

B1390

比沙可啶

analytical standard, for drug analysis

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关于此项目

经验公式(希尔记法):
C22H19NO4
化学文摘社编号:
分子量:
361.39
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
210-044-4
MDL number:
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InChI key

KHOITXIGCFIULA-UHFFFAOYSA-N

InChI

1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3

SMILES string

CC(=O)Oc1ccc(cc1)C(c2ccc(OC(C)=O)cc2)c3ccccn3

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

Quality Level

Gene Information

human ... CHRM4(1132)

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General description

Bisacodyl is a diphenylmethane derivative, mainly used as a stimulant laxative for treating constipation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Michael A Kamm et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 9(7), 577-583 (2011-03-29)
Although stimulant laxatives have been used for many years to treat patients with constipation, their clinical value has been questioned, and there have been few high-quality trials to assess their efficacy. We tested the efficacy and safety of 4 weeks
V Giorgio et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 25(1), 70-78 (2012-10-04)
Severe pediatric slow transit constipation (STC) is commonly due to intrinsic colonic neuromuscular disease. We sought to correlate neuromuscular histological phenotypes in pediatric STC with colonic manometric phenotypes using high-resolution manometry (HRM). We tested the hypothesis that failure of motor
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk (2011)
Mercedes Ibáñez et al.
Diseases of the colon and rectum, 54(12), 1578-1584 (2011-11-10)
No consensus exists regarding the optimal bowel preparation regimen for patients with poor bowel cleansing at a previous colonoscopy. We investigated the usefulness of an intensive cleansing regimen for repeat colonoscopy after previous failure of bowel preparation. A prospective observational
Stephen Vanner et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 663-666 (2011-12-17)
Despite the wealth of research investigating bowel cleansing efficacy, there are very little data on the timing or frequency of bowel movements after each agent is ingested. To examine the effect of each component of a three-day combined sodium picosulphate⁄magnesium

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