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Merck
CN

B5887

丁酸钠

≥98.5% (GC)

别名:

丁酸 钠盐

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关于此项目

线性分子式:
CH3CH2CH2COONa
化学文摘社编号:
156-54-7
分子量:
110.09
UNSPSC Code:
12352107
NACRES:
NA.25
PubChem Substance ID:
24891873
EC Number:
205-857-6
Beilstein/REAXYS Number:
3629439
MDL number:
MFCD00002816

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产品名称

丁酸钠, ≥98.5% (GC)

biological source

synthetic (organic)

InChI key

MFBOGIVSZKQAPD-UHFFFAOYSA-M

InChI

1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1

SMILES string

[Na+].CCCC([O-])=O

assay

≥98.5% (GC)

form

powder

storage condition

(Tightly closed. Dry.
Keep in a dry place. )

technique(s)

DNA amplification: suitable
cell based assay: suitable
inhibition assay: suitable

color

white

mp

250-253 °C (lit.)

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

cation traces

Na: 19.8-22.0% (anhydrous)

suitability

suitable for DNA precipitation

application(s)

cell analysis
life science and biopharma
lipidomics

storage temp.

room temp

Quality Level

200

Gene Information

mouse ... ENSMUSG00000061062(15181)

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Application

丁酸钠已可用于：
  • 作为匀浆和免疫沉淀缓冲液的一种成分，在果蝇胚胎和昆虫s2细胞中抑制HDAC。
  • 以组蛋白脱乙酰酶抑制剂MDA-MB-231作为乳腺癌细胞株的抑制因子，采用细胞活力法和病毒复制法进行分析。
  • 提高生物反应器中中国仓鼠卵巢（CHO）细胞中重组组织纤溶酶原激活剂(t-PA)的产量。

Biochem/physiol Actions

丁酸钠是一种短链脂肪酸，在毫摩尔范围内抑制组蛋白脱乙酰酶(HDAC)。减少细胞内Ca2+ 的释放。诱导数种细胞系的凋亡。丁酸钠诱导中国仓鼠卵巢(CHO)细胞和其他人类细胞系产生重组蛋白。丁酸钠影响细胞内的蛋白质组和基因表达通路。它抑制细胞周期相关基因，并修饰参与细胞代谢和凋亡的基因。

Disclaimer

吸湿

Other Notes

如需了解生化试剂系列的更多信息，请填写此表。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000496278
0000496279
0000496279
0000496278
0000494337

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