Merck
CN
所有图片(1)

文件

C0414

Supelco

克利溴铵

analytical standard

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别名:
可立啶
经验公式（希尔记法）:
C22H26BrNO3
CAS号:
3485-62-9
分子量:
432.35
EC 号:
222-471-3
MDL编号:
MFCD00078996
PubChem化学物质编号:
329774786
NACRES:
NA.24

等级

analytical standard

质量水平

200

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

格式

neat

SMILES字符串

Br.C[N]12CCC(CC1)C(C2)OC(=O)C(O)(c3ccccc3)c4ccccc4

InChI

1S/C22H26NO3.BrH/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,17,20,25H,12-16H2,1H3;1H

InChI key

WVDSMJSQJXGCNY-UHFFFAOYSA-N

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相关类别

一般描述

Clidinium bromide is an anticholinergic, antisecretory and antispasmodic drug, widely used in treating anxiety-related conditions and spastic colon by inhibiting the action of parasympathetic innervations thus decreasing the secretions of stomach acid and slowing the intestines.

应用

Clidinium bromide has been used as an analytical standard for the quantification of the analyte in pharmaceutical formulations using different analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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L Mei et al.
The Journal of pharmacology and experimental therapeutics, 251(1), 90-97 (1989-10-01)
We studied the relationship between the M1 muscarinic receptor density and the receptor-mediated hydrolysis of inositol lipids in cloned murine fibroblast B82 cells which were transfected with the m1 muscarinic receptor gene. Of the seven clones examined, the M1 muscarinic
Method development and validation of RP-HPLC method for simultaneous estimation of clidinium bromide, chlordiazepoxide and dicyclomine hydrochloride in bulk and combined tablet dosage forms
Doki.A and SK.K
International Journal of Pharma and Bio Sciences, 3(3), 152-161 (2013)
F J Ehlert et al.
The Journal of pharmacology and experimental therapeutics, 255(3), 1148-1157 (1990-12-01)
The distribution of subtypes of the muscarinic receptor in homogenates of the rat brain was investigated by measuring the competitive inhibition of the binding [3H]N-methylscopolamine by pirenzepine and AF-DX 116 (11[[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5, 11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-one). In most brain regions, the competitive binding curves
J Delforge et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 34(6), 981-991 (1993-06-01)
The potential for noninvasive quantification of myocardial muscarinic receptors using PET data, a mathematical model, multi-injection protocols and 11C-labeled methylquinuclidinyl benzilate (MQNB) as a radioligand was previously demonstrated in dogs. The present study examines the possibility of optimizing the experimental
B Nickerson
Journal of pharmaceutical and biomedical analysis, 15(7), 965-971 (1997-04-01)
A capillary electrophoresis (CE) method utilizing indirect ultraviolet (UV) detection was developed for the determination of a non-UV absorbing degradation product, Ro 5-5172, in clidinium bromide drug substance. The electrophoresis buffer consisted of sodium phosphate and benzyltrimethylammonium bromide. Rinsing the
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