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文件

C1510000

洗必泰

Name: 洗必泰
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

1,1'-己基双[5-(对氯苯基)双胍]

线性分子式:

[-(CH₂)₃NHC(=NH)NHC(=NH)NHC₆H₄Cl]₂

CAS号:

55-56-1

分子量:

505.45

Beilstein:

2826432

MDL编号:

MFCD00009673

PubChem化学物质编号:

329774893

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

chlorhexidine

制造商/商品名称

EDQM

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

134-136 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

InChI key

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Chlorhexidine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Danger

危险声明

H318 - H410

预防措施声明

P273 - P280 - P305 + P351 + P338 - P391 - P501

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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Reduced susceptibility to chlorhexidine in staphylococci: is it increasing and does it matter?

Carolyne Horner et al.

The Journal of antimicrobial chemotherapy, 67(11), 2547-2559 (2012-07-27)

Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical

Impact of non-rinse skin cleansing with chlorhexidine gluconate on prevention of healthcare-associated infections and colonization with multi-resistant organisms: a systematic review.

S Karki et al.

The Journal of hospital infection, 82(2), 71-84 (2012-08-15)

The topical use of chlorhexidine gluconate (CHG) is intended to reduce bacterial density on patients' skin. To assess the impact of body bath or skin cleansing with CHG-impregnated or CHG-saturated washcloths in preventing healthcare-associated infections and colonization. This systematic review

Selective digestive or oropharyngeal decontamination and topical oropharyngeal chlorhexidine for prevention of death in general intensive care: systematic review and network meta-analysis.

Richard Price et al.

BMJ (Clinical research ed.), 348, g2197-g2197 (2014-04-02)

To determine the effect on mortality of selective digestive decontamination, selective oropharyngeal decontamination, and topical oropharyngeal chlorhexidine in adult patients in general intensive care units and to compare these interventions with each other in a network meta-analysis. Systematic review, conventional

The forgotten role of alcohol: a systematic review and meta-analysis of the clinical efficacy and perceived role of chlorhexidine in skin antisepsis.

Matthias Maiwald et al.

PloS one, 7(9), e44277-e44277 (2012-09-18)

Skin antisepsis is a simple and effective measure to prevent infections. The efficacy of chlorhexidine is actively discussed in the literature on skin antisepsis. However, study outcomes due to chlorhexidine-alcohol combinations are often attributed to chlorhexidine alone. Thus, we sought

Effects of intra-alveolar placement of 0.2% chlorhexidine bioadhesive gel on dry socket incidence and postsurgical pain: a double-blind split-mouth randomized controlled clinical trial.

Afshin Haraji et al.

Journal of orofacial pain, 27(3), 256-262 (2013-07-25)

To assess the effects of intra-alveolar application of chlorhexidine gel on the incidence of alveolar osteitis (dry socket) and the severity of postsurgical pain. A total of 160 impacted mandibular third molars were extracted in 80 patients enrolled in this

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