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Merck
CN

C1528

可卡因 盐酸盐 溶液

1.0 mg/mL in methanol, analytical standard, for drug analysis

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关于此项目

经验公式（希尔记法）:
C17H21NO4 · HCl
化学文摘社编号:
53-21-4
分子量:
339.81
NACRES:
NA.24
PubChem Substance ID:
329774894
UNSPSC Code:
41116107
MDL number:
MFCD00058119

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InChI key

PIQVDUKEQYOJNR-VZXSFKIWSA-N

SMILES string

Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3

InChI

1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1

drug control

Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IB (Portugal), kontrollierte Droge in Deutschland

Quality Level

200

concentration

1.0 mg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

相关类别

General description

可卡因通常以盐酸可卡因的形式获得，它是白色至类白色粉末。它是通过鼻内途径服用的。在某些手术中用作局部麻醉药物。

Application

使用盐酸可卡因溶液作为校准标准品，使用气相色谱/质谱法（GC/MS）测定人发样品中的可卡因。可作为dragendorff试剂结合纸喷雾电离质谱法定量分析可卡因及其掺杂物如利多卡因和livamisole的标准品。

Other Notes

有关合适的仪器技术的更多信息，请参阅产品′分析证书。想要获得更多支持，请联系技术服务部。

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000521588
0000521588
0000456027
0000456027
0000433618

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Quantification of cocaine and its adulterants (lidocaine and levamisole) using the Dragendorff reagent allied to paper spray ionization mass spectrometry
Santos.H, et al.
Analytical Methods : Advancing Methods and Applications (2017)
L Skender et al.
Forensic science international, 125(2-3), 120-126 (2002-03-23)
Hair of young subjects (N = 36) suspected for drug abuse was analysed for morphine, codeine, heroin, 6-acetylmorphine, cocaine, methadone, amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxyethylamphetamine (MDEA). The analysis of morphine, codeine, heroin, 6-acetylmorphine, cocaine, and methadone in
Elena Martín-García et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(10), 2317-2330 (2014-03-19)
High-frequency intake and high drug-induced seeking are associated with cocaine addiction in both human and animals. However, their relationships and neurobiological underpinnings remain hypothetical. The medial prefrontal cortex (mPFC), basolateral amygdala (BLA), and nucleus accumbens (NAc) have been shown to
Billy T Chen et al.
Nature, 496(7445), 359-362 (2013-04-05)
Loss of control over harmful drug seeking is one of the most intractable aspects of addiction, as human substance abusers continue to pursue drugs despite incurring significant negative consequences. Human studies have suggested that deficits in prefrontal cortical function and
John W Muschamp et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), E1648-E1655 (2014-04-08)
Hypocretin (orexin) and dynorphin are neuropeptides with opposing actions on motivated behavior. Orexin is implicated in states of arousal and reward, whereas dynorphin is implicated in depressive-like states. We show that, despite their opposing actions, these peptides are packaged in
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实验方案

HPLC Analysis of Drugs on Ascentis® Express HILIC

Analytical standards for drug analysis including heroin, cocaine, amphetamine, and methylenedioxymethamphetamine.

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