产品名称
克罗米通, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+
SMILES string
CCN(C(=O)\C=C\C)c1ccccc1C
InChI key
DNTGGZPQPQTDQF-XBXARRHUSA-N
grade
pharmaceutical primary standard
description
predominantly trans
API family
crotamiton
manufacturer/tradename
EDQM
refractive index
n20/D 1.54 (lit.)
bp
153-155 °C/13 mmHg (lit.)
density
0.987 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Application
Crotamiton EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
Allergic contact dermatitis due to crotamiton.
H Hara et al.
Contact dermatitis, 49(4), 219-219 (2004-03-05)
Scabies.
Godfrey Walker et al.
Clinical evidence, (7)(7), 1543-1548 (2002-09-17)
Kyoung-Jin Kim et al.
Pediatric dermatology, 19(5), 409-411 (2002-10-18)
Misdiagnosis is frequent in scabies of infants and children because of a low index of suspicion, secondary eczematous changes, and inappropriate therapy. Topical or systemic corticosteroids may modify the clinical presentation of scabies and that situation is referred to as
Demodecidosis manifested on the external genitalia.
S M Hwang et al.
International journal of dermatology, 37(8), 634-636 (1998-09-10)
Ulrich R Hengge et al.
The Lancet. Infectious diseases, 6(12), 769-779 (2006-11-25)
Scabies has been a scourge among human beings for thousands of years. Its worldwide occurrence with epidemics during war, famine, and overcrowding is responsible for an estimated 300 million people currently infested. Scabies refers to the various skin lesions produced
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