CN
一般描述
IV型胶原酶(Cls IV)属于哺乳动物细胞外中性金属蛋白酶家族成员。消化基底膜的主要组成成分——IV型胶原蛋白。
该产品与Biochrom GmbH部件号C4-22和C4-28相同。由胶原酶、梭菌蛋白酶混合而成的酶，具有胰蛋白酶和蛋白水解活性。推荐用于分离朗格汉斯岛。比活度为每毫克粉末物质125至250 Mandl单位。
应用
IV型胶原酶(Cls IV)用途：
- 作为杜氏改良Eagle培养基(DMEM)/F12组分，用于消化来自体外受精(IVF)患者的子宮內膜标本
- 用于胶原酶肝脏灌流法分离大鼠肝细胞
- 用于分离大鼠肾小球内皮细胞(GEndCs)
法规信息
常规特殊物品
常规特殊物品
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Yulia Gnainsky et al.
Fertility and sterility, 94(6), 2030-2036 (2010-03-27)
To study whether an injury-induced inflammation might be the mechanism underlying the favorable effect of endometrial biopsy on the implantation rate in in vitro fertilization (IVF) patients. Controlled clinical study. A medical center IVF unit and a research institute. Women
Liquan Jin et al.
Molecular medicine reports, 27(3) (2023-02-18)
The present study aimed to identify the function and expression of trimethylated protein histone H3 lysine 36 (H3K36)me3 and the upstream specific enzyme histone methyltransferase SET domain containing 2 (SETD2), during the differentiation of hepatic oval cells (HOCs) into cholangiocytes
Mingtai Gui et al.
Experimental and therapeutic medicine, 22(6), 1446-1446 (2021-11-02)
Continuous and irreversible cardiac hypertrophy can induce cardiac maladaptation and cardiac remodeling, resulting in increased risk of developing cardiovascular diseases. The present study was conducted to investigate the therapeutic effect of Huoxue Qianyang Qutan recipe (HQQR) on angiotensin II (Ang
Sina M Schalbetter et al.
Science advances, 8(9), eabi6672-eabi6672 (2022-03-03)
The prefrontal cortex (PFC) is a cortical brain region that regulates various cognitive functions. One distinctive feature of the PFC is its protracted adolescent maturation, which is necessary for acquiring mature cognitive abilities in adulthood. Here, we show that microglia
P Huhtala et al.
The Journal of biological chemistry, 265(19), 11077-11082 (1990-07-05)
The structure of the gene for human 70-kDa type IV collagenase (gelatinase) was determined. Three overlapping genomic clones were isolated and shown to contain 0.4 kilobase (kb) of the 5'-flanking region, the 27-kb structural gene, and 4.5 kb of the
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