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Merck
CN

D0501

4-脱氧吡哆醇 盐酸盐

analytical standard

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关于此项目

经验公式(希尔记法):
C8H11NO2 · HCl
化学文摘社编号:
分子量:
189.64
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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生物来源

synthetic (organic)

质量水平

等级

analytical standard

方案

≥98%

技术

HPLC: suitable
gas chromatography (GC): suitable

颜色

white to yellow

mp

263-265 °C

应用

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

包装形式

neat

储存温度

−20°C

SMILES字符串

Cl.Cc1ncc(CO)c(C)c1O

InChI

1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H

InChI key

QZKKOQQIVLXUEI-UHFFFAOYSA-N

一般描述

4-脱氧吡哆醇盐酸盐是维生素 B6 的强效拮抗剂。

应用

4-脱氧吡哆醇盐酸盐分析标准品的用途如下:
  • 开发反相高效液相色谱 (RP-HPLC)-质谱 (MS) 方法联用检测,进行美他多辛药物的杂质分析
  • 用作超高效和高效液相色谱分析的内标,与紫外、质谱和荧光检测器联用分析复合维生素片剂样品中的吡哆醇

其他说明

有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A Trakatellis et al.
Postgraduate medical journal, 68 Suppl 1, S70-S77 (1992-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme was very low. Under the influence of mitogenic stimuli serine hydroxymethyl-transferase activity was induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine, a
J Scountzou et al.
Immunopharmacology and immunotoxicology, 11(4), 657-666 (1989-01-01)
We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (PHA)
HPLC analysis of vitamin B6 in foods
Ollilainen, V-M
Agricultural and food science, 8(6), 515-619 (1999)
Hong Chen et al.
Fish & shellfish immunology, 19(3), 241-252 (2005-04-12)
A feeding experiment was conducted to investigate the effects of dietary pyridoxine (PN) on the immune responses of abalone, Haliotis discus hannai Ino. Purified diets supplemented with 0, 40, 800 mg PN kg(-1) or 80 mg kg(-1) of 4-deoxypyridoxine (PN
W F Wolkers et al.
The Journal of biological chemistry, 266(31), 20761-20766 (1991-11-05)
The distances between enzyme-bound paramagnetic CrATP (a stable, beta, gamma-bidentate complex of Cr3+ and ATP) at the active site of sheep brain pyridoxal kinase and the protons of bound inhibitor 4-dPyr (4-deoxypyridoxine) were determined in the ternary enzyme-CrATP.4-dPyr complex by

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