生物来源
synthetic (organic)
质量水平
等级
analytical standard
方案
≥98%
技术
HPLC: suitable
gas chromatography (GC): suitable
颜色
white to yellow
mp
263-265 °C
应用
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
包装形式
neat
储存温度
−20°C
SMILES字符串
Cl.Cc1ncc(CO)c(C)c1O
InChI
1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H
InChI key
QZKKOQQIVLXUEI-UHFFFAOYSA-N
一般描述
4-脱氧吡哆醇盐酸盐是维生素 B6 的强效拮抗剂。
应用
4-脱氧吡哆醇盐酸盐分析标准品的用途如下：
- 开发反相高效液相色谱 (RP-HPLC)-质谱 (MS) 方法联用检测，进行美他多辛药物的杂质分析
- 用作超高效和高效液相色谱分析的内标，与紫外、质谱和荧光检测器联用分析复合维生素片剂样品中的吡哆醇
其他说明
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
R A Campbell et al.
Life sciences, 48(3), 225-235 (1991-01-01)
DL-alpha-difluoromethylornithine (DFMO), 4-deoxypyridoxine (4-DOP), and methylglyoxal bis (guanylhydrazone) (MGBG) were tested as inhibitors of acute skin graft rejection. Proximal full thickness tail skins were exchanged between C57BL/6 and Balb/C mice. Distal autografts were placed to monitor healing. Inhibitors were given
A Trakatellis et al.
Postgraduate medical journal, 70 Suppl 1, S89-S92 (1994-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme is very low. Under the influence of mitogenic stimuli serine hydroxymethyltransferase activity is induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine (dB6)
C I Levene et al.
The International journal of biochemistry, 20(12), 1451-1456 (1988-01-01)
1. Treatment of chick embryos with two lathyrogens lowered lysyl oxidase and increased collagen extractability. 2. Subsequent treatment with pyridoxal restored both parameters towards normal, whereas PQQ treatment was less effective. 3. These results suggest the requirement of a pyridoxal
N E Andén et al.
Pharmacology & toxicology, 60(5), 393-396 (1987-05-01)
Experimentally induced changes in the concentration of GABA were studied in regions where GABA is present, predominantly in nerve terminals (substantia nigra, pituitary gland) or outside nerve terminals (corpus callosum). Some other regions (cerebellum, cuneate nucleus, corpus striatum, hippocampus) were
M Lorenzato et al.
Methods and findings in experimental and clinical pharmacology, 9(10), 649-656 (1987-10-01)
The study was performed with isolated perfused isovolumic rat hearts. After a 40 min stabilization period, the effect of 4-deoxypyridoxine (DOP) 10(-5) M was studied with 3 Glc concentrations: 0, 3.3 and 11 mM. DOP was perfused during a 20
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