D0501
4-脱氧吡哆醇 盐酸盐
analytical standard
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关于此项目
经验公式（希尔记法）:
C8H11NO2 · HCl
化学文摘社编号:
分子量:
189.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
205-714-8
MDL number:
InChI
1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H
InChI key
QZKKOQQIVLXUEI-UHFFFAOYSA-N
SMILES string
Cl.Cc1ncc(CO)c(C)c1O
biological source
synthetic (organic)
grade
analytical standard
assay
≥98%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
white to yellow
mp
263-265 °C
application(s)
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
format
neat
storage temp.
−20°C
Quality Level
General description
4-脱氧吡哆醇盐酸盐是维生素 B6 的强效拮抗剂。
Application
4-脱氧吡哆醇盐酸盐分析标准品的用途如下：
- 开发反相高效液相色谱 (RP-HPLC)-质谱 (MS) 方法联用检测，进行美他多辛药物的杂质分析
- 用作超高效和高效液相色谱分析的内标，与紫外、质谱和荧光检测器联用分析复合维生素片剂样品中的吡哆醇
Other Notes
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
HPLC analysis of vitamin B6 in foods
Ollilainen, V-M
Agricultural and food science, 8(6), 515-619 (1999)
A Trakatellis et al.
Postgraduate medical journal, 68 Suppl 1, S70-S77 (1992-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme was very low. Under the influence of mitogenic stimuli serine hydroxymethyl-transferase activity was induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine, a
J Scountzou et al.
Immunopharmacology and immunotoxicology, 11(4), 657-666 (1989-01-01)
We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (PHA)
V E Allgood et al.
The Journal of biological chemistry, 265(21), 12424-12433 (1990-07-25)
We have examined the influence of intracellular vitamin B6 concentration on glucocorticoid receptor function in HeLa S3 cells transfected with a glucocorticoid-responsive chloramphenicol acetyltransferase (CAT) reporter plasmid. CAT activity is induced from this plasmid specifically by glucocorticoid hormones in a
S P Coburn et al.
The Journal of nutrition, 119(2), 181-188 (1989-02-01)
In previous work identification of urinary metabolites of 4'-deoxypyridoxine which had been oxidized in the 5'-position and long-term dilution of labeled urinary metabolites with unlabeled molecules suggested possible microbial contributions. In the current studies germfree guinea pigs were able to
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