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Merck
CN

D6518

二乙烯三胺五醋酸

≥99% (titration)

别名:

DETAPAC, DTPA, 二乙三胺五乙酸, 二乙三胺五醋酸, 二乙烯三胺五醋酸, 二亚乙基三胺五乙酸

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关于此项目

线性分子式:
[(HOOCCH2)2NCH2CH2]2NCH2COOH
化学文摘社编号:
分子量:
393.35
UNSPSC Code:
12352106
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-652-8
Beilstein/REAXYS Number:
1810219
MDL number:
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产品名称

二乙烯三胺五醋酸, ≥99% (titration)

InChI key

QPCDCPDFJACHGM-UHFFFAOYSA-N

InChI

1S/C14H23N3O10/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O

biological source

synthetic (organic)

assay

≥99% (titration)

form

powder

mp

219-220 °C (lit.)

solubility

1 M HCl: 50 mg/mL, clear, colorless

storage temp.

room temp

Quality Level

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General description

二乙烯三胺五乙酸是一种多二乙烯三胺五乙酸酐,它是一种双功能螯合剂。它用于治疗中毒。

Preparation Note

纯化

Application

二乙烯三胺五乙酸已被用于:
  • 丝切蛋白活性测定
  • 测定超氧化物在主动脉缩窄(TAC)心脏中的特异性
  • 铕微球检测分析
  • 检测胸腺细胞中还原的 (S- 活性) 或不可逆氧化的(SO3H无活性)酪氨酸蛋白磷酸酶非受体6型(SHP-1)。

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

target_organs

Respiratory Tract

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

392.0 °F - closed cup

flash_point_c

200 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. How can I get Product D6518, Diethylenetriaminepentaacetic acid, to dissolve?

    As is the case with other chelating agents such as EDTA and EGTA, the solubility of DTPA is a function of pH.  Therefore, this compound can be solubilized with either the addition of acid such as a hydrochloric acid solution or (more likely) base such as a sodium hydroxide solution .

  6. What are the pKa values for Product D6518, Diethylenetriaminepentaacetic acid?

    The pKa values for the carboxyl groups as reported in the reference book "Data for Biochemical Research, 3rd ed., page 402, Oxford University Press, New York (1986)." are 1.8, 2.6, 4.4, 8.8, and 10.4.

  7. What cations can be chelated with Product D6518, Diethylenetriaminepentaacetic acid (DTPA)?

    DTPA forms stable complexes with most divalent and trivalent cations.  Some examples are Fe3+, Cu2+, Ni2+, Pb2+, Zn2+, Fe2+, Mn2+, Ca2+,  Mg2+, and Ba2+.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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