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Merck
CN

E9876

乙氢去甲奎宁 盐酸盐

analytical standard

别名:

奥普托欣

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关于此项目

经验公式(希尔记法):
C21H28N2O2 · HCl
化学文摘社编号:
分子量:
376.92
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
222-302-3
Beilstein/REAXYS Number:
4055970
MDL number:
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grade

analytical standard

Quality Level

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H][C@@]12CCN(C[C@@H]1CC)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OCC)cc34

InChI

1S/C21H28N2O2.ClH/c1-3-14-13-23-10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-4-2)12-18(17)19;/h5-7,9,12,14-15,20-21,24H,3-4,8,10-11,13H2,1-2H3;1H/t14-,15-,20-,21+;/m0./s1

InChI key

QNRATNLHPGXHMA-XZHTYLCXSA-N

Application

鉴定 Streptococcus pneumoniae 的特效灵敏试剂。
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rehab H Bahy et al.
Jundishapur journal of microbiology, 9(4), e30708-e30708 (2016-06-16)
Streptococcus pneumoniae is still one of the major causes of morbidity and mortality worldwide. The prevalent serotype distribution had shown variation along different studies conducted at different time intervals. In order to efficiently assess the epidemiology of the diseases for
C William Wester et al.
Diagnostic microbiology and infectious disease, 42(4), 263-268 (2002-05-15)
Standard identification of Streptococcus pneumoniae by optochin and bile solubility testing can lead to ambiguous results for certain isolates. Newer bacteriologic identification techniques (e.g., DNA probes) now exist. In a prospective point prevalence study of oropharyngeal S. pneumoniae carriage rates
Kyung Hyo Kim et al.
Clinical and diagnostic laboratory immunology, 10(4), 616-621 (2003-07-11)
For evaluating pneumococcal vaccines, the opsonophagocytic killing assay (OPKA) is useful as a supplement to the pneumococcal antibody enzyme-linked immunosorbent assay (ELISA). However, evaluations of pneumococcal vaccines require the determination of antibody responses to 7 to 11 serotypes, and the
Luz Balsalobre et al.
Antimicrobial agents and chemotherapy, 57(1), 254-260 (2012-11-02)
Fourteen fluoroquinolone-resistant streptococcal isolates with recombinant DNA topoisomerase genes, preliminarily identified as pneumococci, were further characterized using phenotypic and genotypic approaches. Phenotypic tests classified them as atypical pneumococci. Phylogenetic relationships were analyzed by using the sequences of seven housekeeping alleles
Paulo R Cortes et al.
Journal of clinical microbiology, 46(6), 1930-1934 (2008-04-18)
Optochin susceptibility is a key test used for pneumococcal diagnosis, but optochin-resistant (Opt(r)) pneumococci have been reported in the last 2 decades. In this work, we characterized eight Opt(r) clinical strains which presented a new mutation, G47V, a predominant A49S

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