F0888
Fura 2-AM
≥95% purity (HPLC), powder
别名:
Fura 2 五（乙酰氧基甲基）酯
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关于此项目
经验公式（希尔记法）:
C44H47N3O24
化学文摘社编号:
分子量:
1001.85
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
8183748
产品名称
Fura 2-AM, ≥95% (HPLC)
InChI key
VPSRLGDRGCKUTK-UHFFFAOYSA-N
SMILES string
CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccc(C)cc1OCCOc2cc3cc(oc3cc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c4ncc(o4)C(=O)OCOC(C)=O
InChI
1S/C44H47N3O24/c1-25-7-8-32(46(16-39(53)65-20-60-26(2)48)17-40(54)66-21-61-27(3)49)35(11-25)58-9-10-59-36-12-31-13-37(43-45-15-38(71-43)44(57)69-24-64-30(6)52)70-34(31)14-33(36)47(18-41(55)67-22-62-28(4)50)19-42(56)68-23-63-29(5)51/h7-8,11-15H,9-10,16-24H2,1-6H3
assay
≥95% (HPLC)
form
powder
color
yellow to yellow-green
solubility
acetone: 10 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
Quality Level
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Application
Fura 2-AM是一种常用的探针，用于测定完整活细胞中细胞质游离钙的动态变化。
Features and Benefits
使用Fura 2的酯形式作为Fura 2-AM的主要好处有：可渗透细胞。容易载入细胞中。与单波长染料相比，使用Fura 2-AM的另一个优点是，比率信号与以下因素无关：染料浓度。照明强度、光程长度。
General description
Fura 2- am（Fura 2）是一种钙特定比率荧光染料。它也被称为乙酰氧基甲酯。 为了响应钙离子，像Fura 2这样的比例度量染料改变了各自的激发或发射光谱。细胞内钙浓度由不同波长的荧光发射比或激发决定。Fura 2的发射峰在505nm，激发峰在340-380nm之间，是首选的钙指示剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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