F9005
氟芬那酸
analytical standard, for drug analysis
别名:
N-(3-[三氟甲基]苯基)邻氨基苯甲酸, N-(α,α,α-三氟-间甲苯基)邻氨基苯甲酸
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关于此项目
线性分子式:
2-(CF3C6H4NH)C6H4CO2H
化学文摘社编号:
分子量:
281.23
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
208-494-1
MDL number:
产品名称
氟芬那酸, analytical standard, for drug analysis
InChI key
LPEPZBJOKDYZAD-UHFFFAOYSA-N
InChI
1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)
SMILES string
OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
132-135 °C (lit.)
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。
氟芬那酸已被用作使用固态密度泛函理论和太赫兹光谱学研究氟芬那酸的两种明确多晶型（如 I 型和 III 型）的标准品。
General description
氟芬那酸是一种非甾体抗炎药，可作为一种有效的止痛剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Julia C Schwarz et al.
International journal of pharmaceutics, 437(1-2), 83-88 (2012-08-21)
Nanocarriers are highly interesting delivery systems for the dermal application of drugs. Based on a eudermic alkylpolyglycosid nanoemulsions, solid lipid nanoparticles (SLN) and nano-structured lipid carriers (NLC) were prepared by ultrasonic dispersion. The ultrasound preparation technique turned out to be
Antonella Di Pizio et al.
Cellular and molecular life sciences : CMLS, 77(3), 531-542 (2019-06-27)
Human bitter taste receptors (TAS2Rs) are a subfamily of 25 G protein-coupled receptors that mediate bitter taste perception. TAS2R14 is the most broadly tuned bitter taste receptor, recognizing a range of chemically diverse agonists with micromolar-range potency. The receptor is
Conformational origins of polymorphism in two forms of flufenamic acid
Delaney P S, et al.
Journal of Molecular Structure, 1078, 83-89 (2014)
Minsoo Kim et al.
Pharmaceutics, 11(3) (2019-03-22)
Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-DHPs. This study was designed to evaluate
Jon Andoni Sánchez et al.
Immunobiology, 222(2), 241-250 (2016-10-11)
Previous works with autumnalamide reported that Store Operated Calcium (SOC) channels were blocked through mitochondrial modulation. In the present paper we studied the effect of autumnalamide on ionomycin Ca2+ fluxes. Thus, autumnalamide did not modify ionomycin-sensitive intracellular pools while the
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