所有图片(1)

文件

G0340000

格列吡嗪

Name: 格列吡嗪
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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所有图片(1)

别名:

1-环己基-3-{4-[2-(5-甲基吡嗪-2-甲酰胺基)乙基]苯磺酰基}脲

经验公式（希尔记法）:

C₂₁H₂₇N₅O₄S

CAS号:

29094-61-9

分子量:

445.54

MDL编号:

MFCD00072159

PubChem化学物质编号:

329799809

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

glipizide

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3

InChI

1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)

InChI key

ZJJXGWJIGJFDTL-UHFFFAOYSA-N

基因信息

human ... ABCC8(6833) , KCNJ11(3767)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Glipizide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

1292609

1292610

1292631

PHR1813

PHR1814

PHR1815

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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In vitro characterization of a novel polymeric system for preparation of amorphous solid drug dispersions.

Zahra N Mahmoudi et al.

The AAPS journal, 16(4), 685-697 (2014-05-03)

Preparation of amorphous solid dispersions using polymers is a commonly used formulation strategy for enhancing the solubility of poorly water-soluble drugs. However, often a single polymer may not bring about a significant enhancement in solubility or amorphous stability of a

Glipizide: an oral hypoglycemic drug.

G Wensing

The American journal of the medical sciences, 298(1), 69-71 (1989-07-01)

[The clinical pharmacology of Minidiab (glipizide) (a review of the literature)].

A V Shcherbak

Likars'ka sprava, (1)(1), 28-33 (1993-01-01)

[Glipizide--a short-acting sulphonylurea derivative].

J Ogonowski

Przeglad lekarski, 53(9), 666-667 (1996-01-01)

Glipizide is a second generation of sulphonylurea compound, effective in lowering of blood glucose, well-tolerated as well as safe during long-term treatment. Glipizide is the agent characterized by rapid pharmacological action. It is indicated both in monotherapy and combined treatment

Glipizide. A review of the pharmacoeconomic implications of the extended-release formulation in type 2 diabetes mellitus.

R H Foster et al.

PharmacoEconomics, 18(3), 289-306 (2001-01-09)

Glipizide is a second generation sulphonylurea agent that is available in a Gastrointestinal Therapeutic System (GITS) extended-release formulation. Glipizide GITS provides more stable plasma drug concentrations than the immediate-release formulation and the once-daily regimen may optimise patient compliance. In patients

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