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Merck
CN

G6529

L -还原型谷胱甘肽

≥98.0%, BioXtra

别名:

γ-L-谷酰基-L-半胱氨酰-甘氨酸, GSH

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关于此项目

线性分子式:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
化学文摘社编号:
70-18-8
分子量:
307.32
NACRES:
NA.26
PubChem Substance ID:
24895261
UNSPSC Code:
12352209
EC Number:
200-725-4
MDL number:
MFCD00065939
Beilstein/REAXYS Number:
1729812

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产品名称

L -还原型谷胱甘肽, BioXtra, ≥98.0%

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

product line

BioXtra

assay

≥98.0%

form

powder

impurities

≤0.02% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white

mp

192-195 °C (dec.) (lit.)

solubility

H2O: 0.1 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.02%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

2-8°C

Quality Level

200

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相关类别

Application

可在5-10 mM下用于从谷胱甘肽琼脂糖洗脱谷胱甘肽S-转移酶(GST)。

Biochem/physiol Actions

作为内源性抗氧化剂在减少细胞代谢和呼吸爆发期间生成的活性氧方面发挥重要作用。 谷胱苷肽S-转移酶催化异生素、白三烯和其他亲电子分子生成谷胱苷肽硫醚。 谷胱苷肽也和蛋白质半胱氨酸残基形成二硫键。 经由这些机制，它会产生降低抗癌药功效的逆反效应(paradoxical effect)。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

动植物源性产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000491944
0000491972
0000491972
0000491944
0000461966

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the best way to make and store solutions of Product G6529, L-Glutathione reduced?

    Reduced glutathione is soluble in water. However, aqueous solutions readily oxidize in air to oxidized glutathione, GSSG.  Therefore, it is probably best to make fresh solutions for use. Half-lives of reduced glutathione in solution at various pHs and temperatures have been reported. The half-life of reduced glutathione is increased in the presence of a chelating agent. For supporting references, please consult the product information sheet (under Documents, above).

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

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