H102
氟哌啶醇代谢物 II
analytical standard
别名:
(±)-4-(4-Chlorophenyl)-α-(4-fluorophenyl)-4-hydroxy-1-piperidinebutanol, 还原氟哌啶醇
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关于此项目
经验公式（希尔记法）:
C21H25ClFNO2
化学文摘社编号:
分子量:
377.88
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
方案
≥98% (HPLC)
表单
solid
技术
HPLC: suitable
gas chromatography (GC): suitable
颜色
white
溶解性
DMSO: 10 mg/mL
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
OC(CCCN1CCC(O)(CC1)c2ccc(Cl)cc2)c3ccc(F)cc3
InChI
1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2
InChI key
WNZBBTJFOIOEMP-UHFFFAOYSA-N
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
M Aravagiri et al.
Journal of chromatography. B, Biomedical applications, 656(2), 373-381 (1994-06-17)
A simple and highly sensitive liquid chromatographic method with electrochemical detection for the simultaneous determination of haloperidol and its metabolite reduced haloperidol in human plasma has been developed. The sample preparation for the analysis involves a simple one-step extraction procedure
S Ulrich et al.
Journal of chromatography. B, Biomedical applications, 663(2), 289-296 (1995-01-20)
A gas chromatographic method using a HP-5 megabore capillary and nitrogen-phosphorus selective detection for the quantitative analysis of haloperidol (H) and reduced haloperidol (RH) in human serum or plasma is described. A 3-step liquid-liquid extraction is applied. The extraction yield
M S Lee et al.
Psychiatry and clinical neurosciences, 52 Suppl, S193-S198 (1999-01-23)
Along with recent increased interest in the selective serotonin reuptake inhibitors, a number of studies has been undertaken to observe interactions with different drugs. When selective serotonin reuptake inhibitor was administered together with antipsychotics to schizophrenics showing depressive or obsessive
D W Eyles et al.
Psychopharmacology, 116(2), 161-166 (1994-10-01)
In patients taking haloperidol (HP), circulating concentrations of reduced haloperidol (RHP increase disproportionately to the dose or concentration of the parent drug. In the current study, we tested the hypothesis that the nonlinearity is due to preferential saturation of the
L Pan et al.
European journal of clinical pharmacology, 55(8), 599-604 (1999-12-14)
To investigate in vitro which CYP isoforms (CYP1A2, CYP2D6 and CYP3A4) are involved in the biotransformation of haloperidol (HAL) and reduced haloperidol (RHAL). The biotransformation of HAL and RHAL is evaluated by measuring HAL and RHAL remaining after incubation with
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