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Merck
CN

H1428000

羟钴胺

European Pharmacopoeia (EP) Reference Standard

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关于此项目

经验公式（希尔记法）:
C62H89CoN13O15P
化学文摘社编号:
13422-51-0
分子量:
1346.36
UNSPSC Code:
41116107
NACRES:
NA.24

主要文件

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产品名称

羟钴胺, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C62H89N13O14P.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H2,63,77)(H2,64,78)(H2,65,79)(H2,66,80)(H2,67,81)(H2,68,82)(H,69,83)(H,85,86);;1H2/q-2;+2;-1/p-1/t31-,34+,35+,36+,37-,41+,52+,53+,56?,57-,59+,60-,61-,62-;;/m0../s1

InChI key

PJOHJFIDLYDPIZ-PMEYKKDOSA-M

grade

pharmaceutical primary standard

API family

hydroxocobalamin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

相关类别

Application

羟钴胺EP参考标准品的预期用途是欧洲药典规定的实验室测试。

General description

本品按现行药典规定交付。该产品的所有支持信息，包括SDS和任何产品信息宣传页均由药典发行机构制定并发布。如需更多信息和支持，请见现行药典的网站。

Other Notes

可能适用相应的销售限制。

Packaging

本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Erin A Paul et al.
Pediatric nephrology (Berlin, Germany), 28(7), 1135-1139 (2013-03-19)
The cblE disorder is an inherited disorder of vitamin B12 metabolism that results in elevated levels of homocysteine and decreased methionine in body fluids. Renal complications have been reported in patients with cblC disease, but not in those with cblE
I Vaz Matos et al.
Molecular genetics and metabolism, 109(4), 360-365 (2013-06-12)
CblC deficiency produces a combination of methylmalonic aciduria (MMA) and homocystinuria (HCU), and is the most common error of cobalamin metabolism. Patients present a wide spectrum of symptoms, ranging from early severe multisystemic forms, to milder late-onset phenotypes. Cognitive and
G Geldner et al.
Der Anaesthesist, 62(8), 609-616 (2013-08-07)
This is a report on an international non-interventional study of patients exposed to fires with smoke development in closed rooms. The objective of the study was to document clinical symptoms, relevant laboratory values and blood cyanide concentrations from fire victims
Martin Kömhoff et al.
Pediatrics, 132(2), e540-e544 (2013-07-10)
Pulmonary arterial hypertension (PAH) and renal thrombotic microangiopathy (rTMA) are rare diseases in childhood, frequently leading to death and end-stage renal disease, respectively. Their combined occurrence has been reported anecdotally. We investigated the clinical, biochemical, and genetic aspects of 5
Emilie Cornec-Le Gall et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 63(1), 119-123 (2013-11-12)
A 20-year-old man was hospitalized for malignant hypertension, mechanical hemolysis, and kidney failure. Kidney biopsy confirmed glomerular and arteriolar thrombotic microangiopathy. Etiologic analyses, which included ADAMTS13 activity, stool culture, complement factor proteins (C3, C4, factor H, factor I, and MCP
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