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Merck
CN

H4125

Supelco

检皮素

analytical standard

别名:

3′,5,7-三羟基-4′-甲氧基黄酮, 5,7-二羟基-2-(3-羟基-4-甲氧基苯基)-4-苯并二氢吡喃-4-酮

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关于此项目

经验公式(希尔记法):
C16H14O6
化学文摘社编号:
分子量:
302.28
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级

analytical standard

质量水平

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3

InChI key

AIONOLUJZLIMTK-UHFFFAOYSA-N

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一般描述

橙皮素是一种苷元形式的类黄酮,人们还在柑桔果皮中发现这种物质。

应用

使用酶联免疫吸附试验 (ELISA) 技术,在涉及橙皮素对阿霉素耐药 MCF-7 细胞的细胞毒性作用的研究中,橙皮素已被用作标准品。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

生化/生理作用

具有化学预防作用的膳食黄烷酮。

其他说明

此产品我们采用非立体特异性的CAS号。虽然该物质主要由天然对映体构成,但它在溶液中很容易发生消旋作用。因此该产品并不能保证一定是立体特异性的,建议只将其用于非立体特异性分析。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Increasing sensitivity of MCF-7/DOX cells towards doxorubicin by hesperetin through suppression of P-glycoprotein expression
Sarmoko, et al.
Indonesian Journal of Pharmacy, 25, 84-84 (2014)
Manoj Aswar et al.
Pharmacology, biochemistry, and behavior, 124, 101-107 (2014-05-30)
Behavioral, biochemical and gene expression changes were investigated in a rat model of partial sciatic nerve ligation (PSNL) after administration of hesperetin (20, 50mg/kg; p.o.), pregabalin (10mg/kg; p.o.) or vehicle (1 ml/kg, p.o.). Thirty-six animals were randomly divided into six
Benjamin Dilberger et al.
Nutrients, 11(8) (2019-08-16)
(1) Background: Polyphenols (PP) play an important role in the prevention of non-communicable diseases and may contribute to healthy aging. To investigate the molecular and cellular aspects of PP metabolites on longevity with a focus on mitochondrial function, we applied
Fei Ding et al.
Molecular bioSystems, 11(4), 1119-1133 (2015-02-13)
Naturally multifunctional Rutaceae hesperidin and its aglycone hesperetin have a great variety of biopharmaceutical activities, e.g. anti-cancer, anti-inflammatory, antioxidant and antitumor; however, the influence of the molecular structures of hesperidin and hesperetin, and in particular, the structural properties such as
Sobiya Zafar et al.
International journal of pharmaceutics, 477(1-2), 454-468 (2014-12-03)
The present work describes the preparation of sterically stabilize polymeric nanoparticles of mitoxantrone dihydrochloride (MTO) along with an efflux transporter (Pgp/BCRP) inhibitor that enhance the circulation time of nanoparticles and simultaneously surmount the problem of multidrug resistance (MDR). Mitoxantrone dihydrochloride

商品

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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