H9645
对羟基甲基苯丙胺
analytical standard, for drug analysis
别名:
Pholderin
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关于此项目
经验公式（希尔记法）:
C10H15NO
化学文摘社编号:
分子量:
165.23
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
206-725-0
MDL number:
产品名称
对羟基甲基苯丙胺, analytical standard, for drug analysis
InChI key
SBUQZKJEOOQSBV-UHFFFAOYSA-N
InChI
1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3
SMILES string
CNC(C)Cc1ccc(O)cc1
assay
≥98% (TLC)
drug control
Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
−20°C
Quality Level
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Application
有关合适的仪器技术的更多信息，请参阅产品′检验报告。想要获得更多支持，请联系技术服务部。
Biochem/physiol Actions
甲基苯丙胺的代谢物；拟交感神经药
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
T Yamamoto et al.
Journal of analytical toxicology, 13(2), 117-119 (1989-03-01)
A sensitive and specific gas chromatography/mass spectrometry (GC/MS) method has been developed for the simultaneous analysis of methampthetamine and its metabolites (amphetamine, p-hydroxymethamphetamine, and p-hydroxyamphetamine) in monkey urine. The method has been applied to the analysis of urine samples from
O al-Dirbashi et al.
The Analyst, 123(11), 2333-2337 (1999-07-09)
A simple, rapid and highly sensitive high-performance liquid chromatographic method with fluorescence detection for determining the enantiomers of methamphetamine and its major metabolites, amphetamine and p-hydroxymethamphetamine, in urine samples was developed. Using a newly developed reagent for amines, namely, 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl
Noriaki Shima et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 830(1), 64-70 (2005-11-03)
Two conjugates of p-hydroxymethamphetamine (p-OHMA), p-OHMA-glucuronide (p-OHMA-Glu) and p-OHMA-sulfate (p-OHMA-Sul) have been identified in methamphetamine (MA) users' urine by using liquid chromatography-high resolution tandem mass spectrometry (LC-HRMS-MS). The synthesis of p-OHMA-Glu and p-OHMA-Sul, and an LC-MS procedure for the simultaneous
Manfred T Birchler et al.
The Annals of otology, rhinology, and laryngology, 111(12 Pt 1), 1087-1091 (2002-12-25)
We report the case of a 17-year-old man who presented with left-sided Horner's syndrome. Magnetic resonance imaging revealed a spindle-shaped cervical tumor in the left paravertebral space. During operation, a tumor originating from the left sympathetic trunk was found. The
A T Bates et al.
Journal of neurology, neurosurgery, and psychiatry, 58(2), 215-217 (1995-02-01)
Mydriatic responses to eyedrops containing the indirect acting sympathomimetic amines tyramine, hydroxyamphetamine, and pholedrine have been compared in 10 healthy subjects. Pholedrine, the n-methyl derivative of hydroxyamphetamine, at a concentration of 1% had effects similar to those produced by 0.5%
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