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Merck
CN

I1887

吲达帕胺

analytical standard, for drug analysis

别名:

N-(2-甲基-2,3-二氢-1H-吲哚基)-3-氨磺酰基-4-氯-苯甲酰胺

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关于此项目

经验公式(希尔记法):
C16H16ClN3O3S
化学文摘社编号:
分子量:
365.83
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
248-012-7
MDL number:
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Quality Level

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(N)(=O)=O

InChI

1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)

InChI key

NDDAHWYSQHTHNT-UHFFFAOYSA-N

Gene Information

human ... SLC12A3(6559)

General description

Indapamide is a deuretic drug, belonging to the class of benzothiadiazines. It is commonly used for the treatment of hypertension. The drug acts by causing a drop in systolic, diastolic and mean blood pressure.

Application

Indapamide may be used as an internal standard for the quantification of the analyte in pharmaceutical formulations and biological samples using different analytical techniques
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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pictograms

Health hazard

signalword

Warning

Hazard Classifications

Lact. - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Simultaneous estimation of amlodipine besylate and indapamide in a pharmaceutical formulation by a high performance liquid chromatographic (RP-HPLC) method
Patel.BD, et al.
Scientia Pharmaceutica, 80(3), 581-590 (2012)
A selective HPLC method for the determination of indapamide in human whole blood: Application to a bioequivalence study in Chinese volunteers
Hang J-T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(1), 202-205 (2006)
Christopher J Bulpitt et al.
Hypertension (Dallas, Tex. : 1979), 61(1), 89-94 (2012-11-23)
White coat hypertension is considered to be a benign condition that does not require antihypertensive treatment. Ambulatory blood pressure (ABP) was measured in 284 participants in the Hypertension in the Very Elderly Trial (HYVET), a double-blind randomized trial of indapamide



全球贸易项目编号

货号GTIN
I1887-250MG04061833652169
I1887-1G04061826762110
I1887-5G04061833428405