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Merck
CN

IRMM469

3,3′,5-三碘甲状腺氨酸 (T3)

IRMM®, certified reference material

别名:

3,3′,5-三碘代-L-甲状腺原氨酸, O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸, T3, 碘噻罗宁

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关于此项目

经验公式(希尔记法):
C15H12I3NO4
化学文摘社编号:
分子量:
650.97
EC Number:
229-999-3
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
2710227
MDL number:
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InChI

1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChI key

AUYYCJSJGJYCDS-LBPRGKRZSA-N

SMILES string

N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O

grade

certified reference material

agency

IRMM®

mp

234-238 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−70°C

Gene Information

Analysis Note

For more information please see:
IRMM469

Legal Information

IRMM is a registered trademark of European Commission

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Ben Emery et al.
Cell, 138(1), 172-185 (2009-07-15)
The transcriptional control of CNS myelin gene expression is poorly understood. Here we identify gene model 98, which we have named myelin gene regulatory factor (MRF), as a transcriptional regulator required for CNS myelination. Within the CNS, MRF is specifically
J Himms-Hagen
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 4(11), 2890-2898 (1990-08-01)
Energy expenditure for thermogenesis in brown adipose tissue (BAT) serves either to maintain body temperature in the cold or to waste food energy. It has roles in thermal balance and energy balance, and when defective, is usually associated with obesity.
H Mizuma et al.
Circulation research, 88(3), 313-318 (2001-02-17)
Thyroid hormone has been reported to have significant effects on the peripheral vascular system, including relaxation of vascular smooth muscle cells and antiatherosclerotic effects. To exert its biological activity, thyroxine, which is a major secretory product of thyroid gland, needs
E Gunilla Stalenheim
Psychiatry research, 121(3), 281-291 (2003-12-17)
This study is a follow-up investigation of a forensic psychiatric sub-population 6-8 years after forensic psychiatric evaluation. The aim was to examine the long-term validity of biological markers of psychopathy and antisocial behavior over time. Data on criminal records were
R Calvo et al.
The Journal of clinical investigation, 86(3), 889-899 (1990-09-01)
To study the protective effects of maternal thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in congenital hypothyroidism, we gave pregnant rats methimazole (MMI), an antithyroid drug that crosses the placenta, and infused them with three different doses of T4 or T3. The

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