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Merck
CN

L6026

十二烷基硫酸钠

greener alternative

BioXtra, ≥99.0% (GC)

别名:

SDS, 十二烷基硫酸盐 钠盐, 十二烷基硫酸钠, 月桂基硫酸盐 钠盐, 月桂基硫酸钠

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关于此项目

线性分子式:
CH3(CH2)11OSO3Na
化学文摘社编号:
分子量:
288.38
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
Beilstein/REAXYS Number:
3599286
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产品名称

十二烷基硫酸钠, BioXtra, ≥99.0% (GC)

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

biological source

synthetic (oragnic)

description

anionic

product line

BioXtra

assay

≥99.0% (GC)

form

powder

mol wt

micellar avg mol wt 18,000

Quality Level

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

aggregation number

62

impurities

Insoluble matter, passes filter test

loss

≤0.5% loss on drying, HV, 20-25 °C

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

H2O: 0.1 M, clear, colorless

density

0.496 g/cm3

anion traces

chloride (Cl-): ≤0.05%
phosphate (PO43-): ≤0.0001%

cation traces

Al: ≤0.0005%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.02%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.05 at 280 in H2O at 0.1 M
≤0.08 at 260 in H2O at 0.1 M

HLB

40

greener alternative category

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Application

十二烷基硫酸钠已用作:
  • 通过表面等离子体共振评估细胞色素c亲和力的表面活性剂
  • 颗粒增强免疫测定的表面活性剂,以抑制颗粒聚集并增强单个微球偶联
  • 生物膜破坏剂。

阴离子洗涤剂

Features and Benefits

  • 经测试证实重金属污染浓度低,从而确保其适用于各种应用
  • 经测试含痕量阴离子和阳离子
  • 适用于生物化学研究的高纯度产品

General description

十二烷基硫酸钠(SDS)是一种众所周知的阴离子去污剂,在科学研究中广泛用于蛋白质二级和三级结构的变性。它包含一条12个碳原子的非极性链,末端为带负电的硫酸基团。SDS有助于蛋白质的变性和增溶,它是聚丙烯酰胺凝胶电泳等过程的基本试剂,在凝胶电泳中有助于测定蛋白质分子量。此外,SDS可作为一种有机钠盐,并可充当去污剂和蛋白质变性剂的双重角色。它的独特性质在于阴离子表面活性剂的性质,特征在于带负电荷。这种电荷促进了与蛋白质和脂质的相互作用,从而导致胶束结构的形成。这些胶束是SDS能够有效溶解和稳定蛋白质和脂质的关键,便于研究人员在科学研究中对其进行详细研究和处理。SDS的两亲特性来源于一条带负电硫酸根的长链脂肪基团,这种性质使其成为各种生物分子实验和研究中的重要去污剂。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Other Notes

如需了解生化试剂系列的更多信息,请填写此表

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

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Biomedical Devices and Their Applications (2013)
Evaluation of cytochrome c affinity to anionic phospholipids by means of surface plasmon resonance
Stepanov G, et al.
Febs Letters, 583(1), 97-100 (2009)
Lonnie J Lucas et al.
Colloids and surfaces. B, Biointerfaces, 49(2), 106-111 (2006-04-20)
Manufacturers of latex immunoassays have typically added surfactants to improve detection sensitivity and prevent non-specific aggregation of microspheres, which may cause both false positives and negatives during diagnostic testing. There is also growing interest in conducting immunoassays in smaller volumes
Brandon M Childers et al.
Infection and immunity, 81(11), 4112-4120 (2013-08-28)
Biofilm formation and persistence are essential components for the continued survival of pathogens inside the host and constitute a major contributor to the development of chronic wounds with resistance to antimicrobial compounds. Understanding these processes is crucial for control of
Shane Stegeman et al.
Endocrine-related cancer, 22(2), 265-276 (2015-02-12)
The oncogene MDM4, also known as MDMX or HDMX, contributes to cancer susceptibility and progression through its capacity to negatively regulate a range of genes with tumour-suppressive functions. As part of a recent genome-wide association study it was determined that

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