SMILES string
N1(CCCc2c1ccc(c2)C#Cc3ccc(cc3)C(=O)O)C(C)C
InChI key
OWPRYZBCLJMXGR-UHFFFAOYSA-N
InChI
1S/C21H21NO2/c1-15(2)22-13-3-4-19-14-17(9-12-20(19)22)6-5-16-7-10-18(11-8-16)21(23)24/h7-12,14-15H,3-4,13H2,1-2H3,(H,23,24)
assay
≥95% (HPLC)
form
powder
storage temp.
2-8°C
Application
Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.
Biochem/physiol Actions
Strong ligand for retinoic acid receptor proteins
Features and Benefits
LightOx25 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx25 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
Other Notes
Chemical Equivalency 1ea=1mg
Legal Information
LightOx is a trademark of LightOx Ltd.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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商品
Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.
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