M8054
氯化锰 四水合物
meets USP testing specifications
别名:
Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O
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关于此项目
线性分子式:
MnCl2 · 4H2O
化学文摘社编号:
分子量:
197.91
EC 号:
MDL编号:
UNSPSC代码:
12352302
PubChem化学物质编号:
NACRES:
NA.21
Agency
USP/NF
meets USP testing specifications
质量水平
方案
98.0-101.0% dry basis
表单
flakes
mp
58 °C (lit.)
应用
pharmaceutical (small molecule)
SMILES字符串
Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
InChI
1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
InChI key
CNFDGXZLMLFIJV-UHFFFAOYSA-L
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
靶器官
Brain
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
闪点(°F)
does not flash
闪点(°C)
does not flash
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Hiroko Nobuta et al.
Cell stem cell, 25(4), 531-541 (2019-10-05)
Pelizaeus-Merzbacher disease (PMD) is an X-linked leukodystrophy caused by mutations in Proteolipid Protein 1 (PLP1), encoding a major myelin protein, resulting in profound developmental delay and early lethality. Previous work showed involvement of unfolded protein response (UPR) and endoplasmic reticulum
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Jerome A Roth et al.
Neurotoxicology, 35, 121-128 (2013-01-15)
Chronic exposure to Mn results in the development of a neurological disorder known as manganism characterized by neurological deficits resembling that seen in Parkinsonism. Although dopaminergic neurons within the nigrostriatal pathway appear intact, Mn-induced irregularities in DA transmission have been
Anne Bertrand et al.
NeuroImage, 64, 693-702 (2012-09-11)
The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
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