M8277
甲氧胺福林 盐酸盐
analytical standard, for drug analysis
别名:
2-氨基-N-[2-(2,5-二甲氧基苯基)-2-羟乙基]乙酰胺
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关于此项目
经验公式（希尔记法）:
C12H18N2O4 · HCl
化学文摘社编号:
分子量:
290.74
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
InChI
1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
InChI key
MGCQZNBCJBRZDT-UHFFFAOYSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
General description
Midodrine is a prodrug and a long acting α-adrenergic stimulating agent, and forms an active metabolite, desglymidodrine, which causes an elevation of the systemic blood pressure with the reduction in heart rate.
Application
Midodrine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
α-肾上腺素激动剂；血管收缩剂
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
此项目有
Horacio Kaufmann et al.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 22(2), 79-90 (2011-11-03)
There is no widely accepted validated scale to assess the comprehensive symptom burden and severity of neurogenic orthostatic hypotension (NOH). The Orthostatic Hypotension Questionnaire (OHQ) was developed, with two components: the six-item symptoms assessment scale and a four-item daily activity
Stability indicating RP-HPLC assay method for estimation of midodrine hydrochloride in bulk and tablets
Jain.KH, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 9(9), 283-287 (2016)
D B Barber et al.
Spinal cord, 38(2), 109-111 (2000-04-13)
A report of two cases of orthostatic hypotension in acute tetraplegia that were resistant to classic treatment interventions. To discuss the use of midodrine hydrochloride for the treatment of orthostatic hypotension in early tetraplegia. Department of Rehabilitation Medicine, The University
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M8277-1G | 04061826762257 |
| M8277-50MG | 04061833652596 |