N1892
纳多洛尔
analytical standard
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关于此项目
经验公式（希尔记法）:
C17H27NO4
化学文摘社编号:
分子量:
309.40
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
255-706-3
MDL number:
InChI
1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1
InChI key
VWPOSFSPZNDTMJ-UCWKZMIHSA-N
SMILES string
CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Gene Information
human ... ADRB1(153), ADRB2(154)
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
β-肾上腺素阻断剂
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Alessandra Besana et al.
Journal of cardiovascular pharmacology, 59(3), 249-253 (2011-10-28)
Beta-adrenergic receptor antagonists (β-blockers) are the therapy of choice for the long QT syndrome but their efficacy is not homogeneous: propranolol and nadolol are the most effective, whereas metoprolol is associated with more treatment failures. Propranolol has a blocking effect
Ling Wang et al.
The Science of the total environment, 426, 289-295 (2012-04-17)
Beta-blockers, prescribed for the treatment of high blood pressure and for long-term use after a heart attack, have been detected in surface and ground waters. This study examines the photochemical fate of three beta-blockers, atenolol, metoprolol, and nadolol. Hydrolysis accounted
Atrial fibrillation in a LQTS patient with an ICD programmed for managed ventricular pacing: what is the cause?
Robert M Gow et al.
Pacing and clinical electrophysiology : PACE, 35(3), 357-359 (2011-05-25)
Priya Chockalingam et al.
Journal of the American College of Cardiology, 60(20), 2092-2099 (2012-10-23)
The purpose of this study was to compare the efficacy of beta-blockers in congenital long QT syndrome (LQTS). Beta-blockers are the mainstay in managing LQTS. Studies comparing the efficacy of commonly used beta-blockers are lacking, and clinicians generally assume they
Sarah Maud Fischer et al.
International journal of pharmaceutics, 422(1-2), 52-58 (2011-10-27)
The compatibility of fasted state simulated intestinal fluid (FaSSIF) in drug permeation studies employing the phospholipid vesicle-based permeation assay (PVPA) model was confirmed by a set of different integrity indicators. Neither calcein permeability nor electrical resistance were found significantly changed
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