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Merck
CN

N5511

(−)-尼古丁 溶液

1.0 mg/mL, analytical standard, for drug analysis

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关于此项目

经验公式（希尔记法）:
C10H14N2
化学文摘社编号:
54-11-5
分子量:
162.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329818656
MDL number:
MFCD00006369
Beilstein/REAXYS Number:
5733110

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InChI

1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1

SMILES string

CN1CCC[C@H]1c2cccnc2

InChI key

SNICXCGAKADSCV-JTQLQIEISA-N

concentration

1.0 mg/mL in methanol, 1.0 mg/mL

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... CHRNA3(1136), CHRNA4(1137), CHRNB2(1141), CHRNB4(1143), CYP2A6(1548), KCNH1(3756)
mouse ... Chrna7(11441), Chrnb1(11443)
rat ... Chrna1(79557), Chrna2(170945), Chrna4(25590), Chrna7(25302), Chrnb2(54239), Chrnb4(25103)

相关类别

Application

(−)-Nicotine solution has been used as a reference standard in the analysis of nicotine in air affected by second hand smoke using ultra performance liquid chromatography (UPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F

flash_point_c

9.7 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000491120
0000491120
0000489355
0000489355
0000476653

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Assessment of nicotine for second hand smoke exposure in some public places in Romania by UPLC-MS
Bratan A, et al.
Chemistry Central Journal, 8(1), 29-29 (2014)
E-cigarettes, smokers and health policies.
S Nardini et al.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 79(1), 6-7 (2013-06-08)
P Caponnetto et al.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 79(1), 12-19 (2013-06-08)
Cigarette smoking is the leading cause of premature mortality in western countries and it is important for smokers to stop as early as possible. Electronic cigarettes are a popular phenomenon of global proportion. Recent uncontrolled studies, reported that a certain
Shunnosuke Handa
Nihon rinsho. Japanese journal of clinical medicine, 71(3), 482-486 (2013-05-02)
For the habitual smokers with nicotine dependence, it is difficult for them to quit smoking. The nicotine replacement therapy (NRT) is a helpful measure for the persons who want to quit smoking. The concept, medication and practice of the NRT
Katsumasa Miyasato
Nihon rinsho. Japanese journal of clinical medicine, 71(3), 477-481 (2013-05-02)
Nicotine dependence involves both psychological and physiological dependence on nicotine. Evidences suggest that nicotine depends on dopamine for its reinforcing effects. A recent summary description of the clinical aspects of nicotine dependence disorders is provided in the DSM-IV-TR of the
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