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经验公式(希尔记法):
C6H6N2O
化学文摘社编号:
分子量:
122.12
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
EC Number:
202-713-4
Beilstein/REAXYS Number:
383619
MDL number:
产品名称
烟酰胺, meets USP testing specifications
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
SMILES string
NC(=O)c1cccnc1
biological source
synthetic (organic)
agency
USP/NF
meets USP testing specifications
assay
98.5-101.5% dry basis
form
crystals
color
white
mp
128-131 °C (lit.)
application(s)
pharmaceutical (small molecule)
Quality Level
Gene Information
human ... PARP1(142), SIRT2(22933)
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Application
烟酰胺用于:
- 作为胰岛成熟培养基的组分
- 诱导胰岛素分泌细胞分化
- 比较其与孕酮的临床前疗效
Biochem/physiol Actions
烟酰胺是烟酰胺腺嘌呤二核苷酸(NAD+)的主要前体,而NAD+是三磷酸腺苷(ATP)产生过程中的重要辅酶。 烟酰胺缺乏与糙皮病有关。
烟酰胺是维生素B3的酰胺衍生物,是PARP抑制剂
General description
烟酰胺,也称为3-吡啶甲酰胺,是水溶性维生素。在植物、动物性食品和化妆品中广泛存在。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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