N7004
β-烟酰胺腺嘌呤二核苷酸 水合物
≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast
别名:
β-DPN, β-NAD, DPN, NAD, 二磷酸吡啶核苷酸, 辅酶, 辅酶 1, 辅酶 A
选择规格
关于此项目
biological source
yeast
Quality Segment
assay
≥96.5% (HPLC), ≥96.5% (spectrophotometric assay)
form
powder
greener alternative product score
old score: 56
new score: 20
Find out more about DOZN™ Scoring
greener alternative product characteristics
Waste Prevention
Less Hazardous Chemical Syntheses
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Use of Renewable Feedstocks
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
color
white to off-white
application(s)
metabolomics
greener alternative category
storage temp.
−20°C
SMILES string
NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
InChI
1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI key
BAWFJGJZGIEFAR-NNYOXOHSSA-N
Gene Information
human ... ESR1(2099), ESR2(2100)
General description
在生物化学研究中，NAD 是sirtuins、多聚ADP核糖聚合酶和cADP核糖合成酶等酶所必需的辅酶。这些酶的催化活性依赖于NAD+，它们影响多个过程，如蛋白质脱乙酰、DNA修复和细胞信号传导。在代谢组学中，NAD在代谢途径中起到关键作用，这一点令其成为全面理解细胞代谢的关键焦点。NAD 参与其它复杂细胞过程，可作为ADP-核糖基化的底物—，核糖基化是影响蛋白质功能的翻译后修饰。 它也可作为环ADP核糖的前体，环ADP核糖是涉及钙动员 (calcium mobilization)和细胞通讯的第二信使分子。NAD研究为多个领域（包括老化）带来希望，目前研究人员在积极进行老化研究。研究也探索了它对神经退行性疾病和代谢失调的影响。
Application
- 制备用于NAD+代谢组学研究的 NAD+ 标准溶液
- 作为MurI 测定反应部分混合物的成分用于谷氨酸消旋酶反应
- 作为显色染色液的成分用于斑马鱼胚胎的染色
Biochem/physiol Actions
Features and Benefits
Packaging
Preparation Note
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable