产品名称
Folate Vitamers in Frozen Human Serum, NIST®SRM®
grade
certified reference material
packaging
pkg of 3.072 g
manufacturer/tradename
NIST®
technique(s)
mass spectrometry (MS): suitable
application(s)
clinical testing
format
matrix material
storage temp.
-65 to -96°C
Legal Information
NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology
Application
Folate Vitamers standard reference material (SRM) is intended for use in validating methods for determining folate vitamers in human serum, and for qualifying the in-house control materials analyzed using those methods.
General description
A unit of the Folate Vitamers standard reference material (SRM) 3949 consists of one vial each of three materials: low (Level 1), medium (Level 3), and high (Level 2) folates. Each vial contains approximately 1.0 mL of frozen human serum.
SRM_3949_cert
SRM_3949_SDS
SRM_3949_cert
SRM_3949_SDS
Other Notes
- SRM 3949 is intended for research use.
- Details on expiration, storage, safety, usage, and source are provided in the NIST certificate
- Information on biomaterials, disposal, and transport is available in the SDS
Preparation Note
- SRM 3949 is provided as a set of three vials of frozen serum that should be allowed to thaw at room temperature for at least 30 min under subdued light.
- The contents of a vial should then be gently mixed prior to the removal of a test portion for analysis.
- Precautions should be taken to avoid exposure to strong ultraviolet (UV) light and direct sunlight.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品--人源产品
此项目有
Seok-Won Hyung et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1179, 122725-122725 (2021-07-27)
One predominant and bioactive folate vitamer circulating in the blood is 5-methyltetrahydrofolate (5-Me-THF). In this study, a method for the accurate determination of 5-Me-THF in human plasma samples of various volumes was established using isotope dilution ultra-high performance liquid chromatography-mass
Johanna E Camara et al.
Analytical and bioanalytical chemistry, 415(5), 809-821 (2022-12-13)
The US National Institute of Standards and Technology (NIST) developed a Standard Reference Material® (SRM®) 3949 Folate Vitamers in Frozen Human Serum to replace SRM 1955 Homocysteine and Folate in Human Serum. The presence of increased endogenous levels of folic
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