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Merck
CN

O1378

羟考酮标准液 盐酸盐

analytical standard

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关于此项目

经验公式（希尔记法）:
C18H21NO4 · HCl
化学文摘社编号:
124-90-3
分子量:
351.82
NACRES:
NA.24
PubChem Substance ID:
329818896
UNSPSC Code:
41116107
EC Number:
204-717-1
MDL number:
MFCD00137583

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InChI key

MUZQPDBAOYKNLO-RKXJKUSZSA-N

InChI

1S/C18H21NO4.ClH/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10;/h3-4,13,16,21H,5-9H2,1-2H3;1H/t13-,16+,17+,18-;/m1./s1

SMILES string

Cl.[H][C@@]12Oc3c(OC)ccc4C[C@H]5N(C)CC[C@@]1(c34)[C@@]5(O)CCC2=O

grade

analytical standard

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal), kontrollierte Droge in Deutschland

Quality Level

200

Gene Information

human ... OPRM1(4988)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

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相关类别

General description

Oxycodone hydrochloride is an analgesic drug, which is generally used in cancer treatment since it can reduce the pain induced during the treatment.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

μ 和 κ 阿片受体激动剂。

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000521589
0000521589
0000487489
0000487489
0000452791

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Rachel E Martin et al.
eNeuro, 8(4) (2021-07-28)
Opioid drugs are increasingly being prescribed to pregnant women. Such compounds can also bind and activate opioid receptors in the fetal brain, which could lead to long-term brain and behavioral disruptions. We hypothesized that maternal treatment with oxycodone (OXY), the
Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation.
Jonathan R McDaniel et al.
Angewandte Chemie (International ed. in English), 52(6), 1683-1687 (2013-01-03)
Clinical observations on safety and efficacy of OxyContin? administered by rectal route in treating cancer related pain
Li G-C, et al.
Asian Pacific Journal of Cancer Prevention, 12, 2477-2478 (2011)
M Soledad Cepeda et al.
The journal of pain : official journal of the American Pain Society, 14(2), 158-164 (2012-12-21)
Obtaining opioids from multiple prescribers, known as doctor shopping, is 1 example of opioid abuse and diversion. The dual mechanism of action of tapentadol could make tapentadol less likely to be abused than other opioids. The aim of this retrospective
Marco Pravetoni et al.
Journal of medicinal chemistry, 56(3), 915-923 (2012-12-20)
Prescription opioids abuse and associated deaths are an emerging concern in the USA. Vaccination against prescription opioids may provide an alternative to pharmacotherapy. An oxycodone hapten containing a tetraglycine linker at the C6 position (6OXY(Gly)(4)OH) conjugated to keyhole limpet hemocyanin
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