O4755
双羟萘酸奥克太尔
analytical standard
别名:
含 4,4′-亚甲基双(3-羟基-2-萘甲酸) 的 1-甲基-2-(3-羟基苯乙烯基)-1,4,5,6-四氢嘧啶化合物
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经验公式（希尔记法）:
C13H16N2O · C23H16O6
化学文摘社编号:
分子量:
604.65
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CN1CCCN=C1\C=C\c2cccc(O)c2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O
InChI
1S/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+
InChI key
CCOAINFUFGBHBA-UETGHTDLSA-N
一般描述
Oxantel pamoate is a drug used in the treatment of trichuriasis which is highly effective against the helminth of Trichuris sp.
应用
Oxantel pamoate may be used as a reference standard for examining the quality of pharmaceutical dosage forms containing oxantel pamoate (OPA) by reversed-phase high-performance liquid chromatography method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Development and validation of a RP-HPLC method for quality control of oxantel pamoate, pyrantel pamoat and praziquantel in tablets.
Tatar E, et al.
Marmara Pharmaceutical Journal (2015)
G R Rajasekariah et al.
International journal for parasitology, 21(6), 697-702 (1991-10-01)
The common anthelmintics, oxantel, mebendazole, albendazole and pyrantel were assessed for their comparative activity against Trichuris muris in mice. Mice were infected with T. muris and the infection was maintained by a brief cortisone administration during the second week of
Wendelin Moser et al.
The Lancet. Infectious diseases, 18(7), 729-737 (2018-04-21)
Albendazole and mebendazole are commonly used to control hookworm, but have shortcomings in their efficacy profiles. We assessed whether triple drug therapy (TDT) with albendazole, pyrantel pamoate, and oxantel pamoate was more effective than the co-administration of two drugs for
Beatrice Barda et al.
The Lancet. Infectious diseases, 18(8), 864-873 (2018-06-03)
The recommended anthelmintics show low efficacy in a single-dose regimen against Trichuris trichiura. Moxidectin, a new treatment for river blindness, might complement the drug armamentarium for the treatment and control of soil-transmitted helminthiasis. However, its efficacy against T trichiura has
Development of oxantel tablets for pediatric clinical studies: a technical note.
Alles R, et al.
Journal of drug delivery science and technology, 23(6), 623-625 (2013)
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