P0597
毛果芸香碱 硝酸酯
meets USP testing specifications
别名:
毛果芸香碱 硝酸盐
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关于此项目
经验公式（希尔记法）:
C11H16N2O2 · HNO3
化学文摘社编号:
分子量:
271.27
UNSPSC Code:
41116107
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-723-7
Beilstein/REAXYS Number:
4171406
MDL number:
Form:
crystals
Quality level:
Quality Level
agency
USP/NF, meets USP testing specifications
form
crystals
application(s)
pharmaceutical (small molecule)
SMILES string
O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
InChI
1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
InChI key
PRZXEPJJHQYOGF-GNAZCLTHSA-N
Gene Information
human ... CHRM1(1128), CHRM3(1131)
Biochem/physiol Actions
非选择性毒蕈碱型乙酰胆碱受体激动剂。
非选择性毒蕈碱型乙酰胆碱受体激动剂；用于建立癫痫的实验模型。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
存储类别
5.1B - Oxidizing hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Linda Holtman et al.
Epilepsia, 54(4), 589-595 (2013-02-13)
Brain inflammation occurs during epileptogenesis and may contribute to the development and progression of temporal lobe epilepsy. Recently, several studies have indicated that seizures may also increase specific blood plasma cytokine levels in animal models as well as in human
Olav B Smeland et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 33(7), 1090-1097 (2013-04-25)
Although certain metabolic characteristics such as interictal glucose hypometabolism are well established for temporal lobe epilepsy (TLE), its pathogenesis still remains unclear. Here, we performed a comprehensive study of brain metabolism in a mouse model of TLE, induced by pilocarpine-status
Manuela Mazzuferi et al.
Annals of neurology, 74(4), 560-568 (2013-05-21)
Epigenetic mechanisms involved in transcriptional regulation of multiple molecular pathways are potentially attractive therapeutic interventions for epilepsy, because single target therapies are unlikely to provide both anticonvulsant and disease-modifying effects. A selection of epilepsy-related gene expression data sets were retrieved
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P0597-25G | 04061835516728 |
| P0597-5G | 04061833612521 |