P1061
盐酸普罗地芬 盐酸盐
analytical standard, ≥95%
别名:
α-苯基-α-丙基苯乙酸-2-(二乙氨)乙酯, N,N-二乙基氨基乙基 2,2-二苯基戊酸酯, SKF-525A
等级
analytical standard
质量水平
方案
≥95%
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
122-123 °C
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
−20°C
SMILES字符串
Cl.CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2
InChI
1S/C23H31NO2.ClH/c1-4-17-23(20-13-9-7-10-14-20,21-15-11-8-12-16-21)22(25)26-19-18-24(5-2)6-3;/h7-16H,4-6,17-19H2,1-3H3;1H
InChI key
FHIKZROVIDCMJA-UHFFFAOYSA-N
基因信息
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
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应用
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
盐酸普瑞迪芬可用作内标，用气相色谱-质谱联用（GC-MS）测定人尿样中的 O-去甲基曲马多、曲马多和 N-去甲基曲马多镇痛剂。
生化/生理作用
阻断格列本脲敏感 K+ 通道。抑制神经元性一氧化氮合成酶和细胞色素 P450
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
David Fuchs et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158611-158611 (2020-01-10)
Trihydroxyoctadecenoic acids (TriHOMEs) are linoleic acid-derived lipid mediators reported to be dysregulated in obstructive lung disease. In contrast to many other oxylipins, TriHOME biosynthesis in humans is still poorly understood. The association of TriHOMEs with inflammation prompted the current investigation
Amber Woodard et al.
AIMS neuroscience, 6(1), 25-42 (2020-04-29)
Neuronal nitric oxide (nNO) has been shown to affect motor function in the brain. Specifically, nNO acts in part through regulation of dopamine (DA) release, transporter function, and the elicitation of neuroprotection/neurodegeneration of neurons in conditions such as Parkinson's disease
Simultaneous determination of tramadol, O-desmethyltramadol and N-desmethyltramadol in human urine by gas chromatography?mass spectrometry
El-Sayed Y A-A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 926, 9-15 (2013)
Rastislav Jendzelovský et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 8(12), 1716-1723 (2009-12-22)
Photodynamic therapy (PDT) is a flexible multi-target therapeutic approach. One of the main requirements of successful PDT is sufficient intracellular concentration of an applicable photosensitizer. Mechanisms of anticancer drug elimination by tumour cells are mostly linked to the elevated expression
Wan-Ling Chang-Liao et al.
Journal of ethnopharmacology, 141(2), 668-673 (2011-08-23)
Gentiopicroside (GPS) is a secoiridoid glucoside isolated from the ethanol extract of Gentianae Radix with a content of 13%, which has been used for centuries in Chinese as a digestive aid. This study investigates the pharmacokinetics of GPS and its
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