P1250000
去氧肾上腺素 盐酸盐
European Pharmacopoeia (EP) Reference Standard
别名:
(R)-(−)-去氧肾上腺素 盐酸盐, (R)-(−)-1-(3-羟基苯基)-2-甲氨基乙醇 盐酸盐, (R)-(−)-3-羟基-α-(甲氨基乙基)苄醇 盐酸盐
等级
pharmaceutical primary standard
Agency
EP Reference Standard
API类
phenylephrine
制造商/商品名称
EDQM
mp
143-145 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
OC1=CC([C@H](CNC)O)=CC=C1.Cl
InChI
1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChI key
OCYSGIYOVXAGKQ-FVGYRXGTSA-N
基因信息
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
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警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Skin Sens. 1B
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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The Journal of clinical investigation, 130(5), 2630-2643 (2020-02-12)
Arterial cardiovascular events are the leading cause of death in patients with JAK2V617F myeloproliferative neoplasms (MPNs). However, their mechanisms are poorly understood. The high prevalence of myocardial infarction without significant coronary stenosis or atherosclerosis in patients with MPNs suggests that
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Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right
Thomas R Sundermeier et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(8), 3780-3791 (2014-05-09)
Photoreceptor cell death is the proximal cause of blindness in many retinal degenerative disorders; hence, understanding the gene regulatory networks that promote photoreceptor survival is at the forefront of efforts to combat blindness. Down-regulation of the microRNA (miRNA)-processing enzyme DICER1
Joseph Bouskila et al.
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Full-field electroretinography is an objective measure of retinal function, serving as an important diagnostic clinical tool in ophthalmology for evaluating the integrity of the retina. Given the similarity between the anatomy and physiology of the human and Green Monkey eyes
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Carotid endarterectomy (CEA) is often completed with general anesthesia and routine shunting; however, shunting is only required in a small group of at-risk patients to maintain adequate cerebral perfusion. Selective shunting during CEA is performed to normalize cerebral hemodynamics for
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