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P1754

Sigma-Aldrich

TWEEN ® 80

viscous liquid

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别名:
吐温80(TWEEN® 80), POE (20)山梨糖醇酐单油酸酯, 聚乙二醇山梨醇酐单油酸酯, 聚山梨酯 80, 聚氧乙烯山梨糖醇酐单油酸酯
CAS号:
9005-65-6
MDL编号:
MFCD00082107
NACRES:
NA.21

生物来源

Porcine (tallow)
bovine (tallow)

质量水平

200

描述

non-ionic

形式

viscous liquid

分子量

micellar avg mol wt 79,000
average mol wt 1310

组成

Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)

聚集数

60

CMC

0.012 mM (20-25°C)

粘度

400-620 mPa.s

转变温度

cloud point 65 °C

溶解性

water: soluble, clear to slightly hazy, colorless to yellow

密度

1.064 g/cm3

HLB

15

application(s)

cell analysis

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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相关类别

一般描述

吐温® 80 是一种非离子去污剂和表面活性剂，属于山梨聚糖油酸酯。它是一种多功能化合物，常用于各种生物学应用，包括细胞裂解、核分离和细胞分级分离。此外，吐温®80可用于稳定蛋白质，并有助于蛋白质膜研究。其功效来源于聚山梨醇酯基团，该基团的特点是山梨醇和山梨聚糖油酸酯与聚乙二醇链的结合。这些结构特性造就了吐温® 80′的乳化能力和广泛应用。

应用

TWEEN® 80已用于小鼠和大鼠中特异性注射中的药物载体溶液。它已用于测定细菌细胞中酯酶的活性。
用于从哺乳动物细胞系中选择性提取蛋白质、分离细胞核的非离子型去垢剂。

生化/生理作用

TWEEN® 80是一种可助力于蛋白质稳定和蛋白质膜研究的聚山梨醇酯表面活性剂。它常用于进行膜蛋白的提取以及从细胞中进行细胞核分离。

特点和优势

  • 优良的润湿和分散剂
  • 适用于细胞生物学和生物化学研究的多功能表面活性剂

其他说明

For additional information on our range of Biochemicals, please complete this form.

法律信息

TWEEN is a registered trademark of Croda International PLC

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

235.4 °F - closed cup

闪点(°C)

> 113 °C - closed cup

个人防护装备

Eyeshields, Gloves

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  • 如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。

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索取COA

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the Critical Micelle Concentration (CMC) of Product P1754, TWEEN® 80?

    The CMC value is 13-15 mg/Liter. 

  4. Is Product P1754, TWEEN® 80, sterile?

    The product is not sterile. Autoclaving a solution of TWEEN 80 is generally not advised. Sterile filtration is more easily done if the liquid is warmed to about 40°C and alternate portions of hot distilled water and TWEEN 80 are poured through the 0.22 μm filter. The TWEEN 80 will blend and remain in solution.

  5. Is Product P1754, TWEEN® 80, cell culture tested?

    No, P1754 is not cell culture tested, but product P4780 is cell culture tested TWEEN 80.

  6. Is Product P1754, TWEEN® 80, tested for RNase and DNase activity?

    No. Product P1754 is not tested for contaminating RNase and DNase activity.  Product P5188 is a Molecular Biology grade product that has been tested for DNase and RNase.

  7. Is it normal for the color of Product P1754, TWEEN® 80, to change from lot to lot?

    Yes. According to Sigma-Aldrich's specifications, Product No. P1754 can appear bright yellow to yellow with a green cast.  Please see our Specification Sheet for more information.

  8. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  9. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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